AIMC Topic: Synthetic Lethal Mutations
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SLKB: synthetic lethality knowledge base.
Nucleic acids research
Jan 5, 2024
Emerging CRISPR-Cas9 technology permits synthetic lethality (SL) screening of large number of gene pairs from gene combination double knockout (CDKO) experiments. However, the poor integration and annotation of CDKO SL data in current SL databases li...
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