The NIH Common Fund Data Ecosystem (CFDE) program was established to facilitate data accessibility and interoperability across multiple Common Fund (CF) programs, promote collaborations and accelerate discoveries by combining diverse data types from ... read more
OBJECTIVE: Accurate preoperative lateralization of temporal lobe epilepsy (TLE) remains challenging, particularly in cases with subtle or MRI-negative lesions. This study aimed to overcome limitations of conventional MRI by developing a diffusion spe... read more
OBJECTIVES: Autoimmune diseases (ADs) demonstrate a higher prevalence in women than men. Systemic Lupus Erythematosus (SLE) stands out among multiple ADs as an extreme case of the imbalanced sex ratio observed at disease onset, predominantly affectin... read more
Clinica chimica acta; international journal of clinical chemistry
Jan 6, 2026
BACKGROUND: Acute kidney injury (AKI) is a complex multifactorial syndrome characterized by a rapid decline in kidney function, frequently observed in hospitalized and critically ill patients. Despite its high morbidity and mortality, current diagnos... read more
Detecting depression from voice recordings is challenging because acoustic indicators are often highly subtle and vary broadly among individuals. A key drawback of current models is their poor cross-lingual generalization; they often degrade sharply ... read more
OBJECTIVE: To evaluate the utility of a clinical staging model and compared its prognostic performance with an unsupervised machine learning-based stratification method in a real-world cohort of patients with Major Depressive Disorder (MDD). METHODS:... read more
BACKGROUND: Lithium is a core treatment for bipolar disorder (BD), yet clinical response varies across patients. Testing accessible predictors of lithium response is critical for personalization strategies in real-world settings. METHODS: In this cro... read more
Vegetation carbon sequestration plays a crucial role in mitigating global warming and maintaining regional carbon balance. The Yellow River Basin (YRB) is a key region for energy development and ecological conservation in China, yet the driving mecha... read more
Tumor-intrinsic biomarkers alone insufficiently predict pathological complete response (pCR) to neoadjuvant immunochemotherapy (NICT) in non-small cell lung cancer (NSCLC). Artificial intelligence (AI)-based three-dimensional CT-derived body composit... read more
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