Cancer cells face a hostile microenvironment characterized by hypoxia, nutrient deprivation, endoplasmic reticulum (ER) stress, and oxidative imbalance. To cope with these challenges, they activate an interconnected network of adaptive pathways inclu... read more
INTRODUCTION: The high-fat diet (HFD) has complex health implications, shaped by the composition of macronutrients and food sources. However, existing dietary assessment tools lack the precision required for effective risk stratification. OBJECTIVES:... read more
INTRODUCTION: Viruses are abundant biological entities within the gastrointestinal tract (GIT) of ruminants. Current understanding is extensive for bacterial and archaeal communities, but limited for viral communities. OBJECTIVES: The study aimed to ... read more
The spine journal : official journal of the North American Spine Society
Jan 6, 2026
BACKGROUND CONTEXT: The gold standard diagnostic test for Adolescent idiopathic scoliosis (AIS) involves manually measuring the spinal column deformity by determining the Cobb angle on a full-spine X-ray image. This measurement involves a subjective ... read more
Plant science : an international journal of experimental plant biology
Jan 6, 2026
Nutritional deficiencies in crops lead to significant yield losses. Early and accurate detection of these deficiencies is crucial for effective intervention, as it enables timely corrective measures, minimizes crop damage, and ensures optimal product... read more
BACKGROUND AND AIMS: A limited amount of diabetic retinopathy (DR) development can be explained by traditional risk factors. This study aimed to determine the association of artificial intelligence (AI)-assisted retinal vasculature measurement parame... read more
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Jan 6, 2026
BACKGROUND AND PURPOSE: In external beam radiotherapy for prostate cancer, inclusion of the seminal vesicles (SV) in the clinical target volume (CTV) is often complicated by considerable SV motion and deformation. This study aimed to investigate the ... read more
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Jan 6, 2026
BACKGROUND AND PURPOSE: Major adverse cardiovascular events (MACEs) remain a significant concern in esophageal cancer (EC) patients receiving radiotherapy (RT). This study aimed to develop and validate a CCTA-based model for predicting MACEs in this ... read more
Metagenomic sequencing has revolutionised the field of microbial ecology, as it has led to cultivation-independent exploration of complicated microbial communities. The assembly of metagenome-assembled genomes has provided genome-scale information ab... read more
Sepsis, a life-threatening systemic inflammatory syndrome, remains a leading cause of global mortality due to its complex pathophysiology and the lack of specific diagnostic biomarkers. Recent evidence highlights intricate interactions between the gu... read more
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