INTRODUCTION: Autologous costal cartilage calcification (CCC) can impact the course and long-term results of rhinoplasty. Preoperative information about the presence, severity, and pattern of CCC helps to assess donor site suitability and rhinoplasty... read more
Interdisciplinary sciences, computational life sciences
Oct 27, 2025
PURPOSE: Traditional Chinese medicine (TCM) has garnered increasing attention from the global medical community due to its unique therapeutic principles and extensive medicinal resources. Understanding herb-target interactions (HTIs) is crucial for e... read more
Pediatric nephrology (Berlin, Germany)
Oct 27, 2025
This brief, focused review considers two of the more commonly used artificial intelligence (AI) methods encountered in nephrology publications: machine vision based on convolutional neural networks (CNNs) and chatbots, such as ChatGPT, based on large... read more
BACKGROUND: Colony-stimulating factor-1 receptor (CSF1R) signaling is crucial for the ability of tumor-associated macrophages (TAMs) to establish an immunosuppressive tumor microenvironment (TME), highlighting the potential of CSF1R signaling as a th... read more
Supervised deep learning methods have been widely employed to detect floating macroplastic litter (>5 mm) in (fresh)water bodies. However, few studies used them to quantify floating litter fluxes in rivers with wide cross-sections, that is important ... read more
Opioids are often prescribed to treat chronic and post-operative pain, but there is data to suggest that opioid exposure can lead to hyperalgesia or allodynia, referring to increases in pain sensitivity to painful and innocuous stimuli, respectively.... read more
INTRODUCTION: Traditional registration process of robotic root canal localization remains cumbersome. This study aimed to determine optimal point cloud registration strategies for robotic root canal localization and evaluate its accuracy. METHODS: 3D... read more
INTRODUCTION: Acute lymphoblastic leukemia (ALL) is a highly heterogeneous hematologic malignancy with poor prognosis in refractory and relapsed cases. Aurora kinase B (AURKB), a member of the Aurora kinase family, is markedly overexpressed in ALL pa... read more
INTRODUCTION: Identifying cell types is a key step in single-cell RNA sequencing data analysis that aids in understanding cellular heterogeneity and facilitates downstream analyses such as those concerning cell-cell interactions and data integration.... read more
Computer methods and programs in biomedicine
Oct 27, 2025
BACKGROUND AND OBJECTIVE: Automated sperm analysis systems rely on machine learning models, which must be trained on large and diverse datasets. However, obtaining real labelled microscopic samples is a costly, time-consuming process, often limited b... read more
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