Artificial Intelligence Medical Compendium

AlphaFold (AF) is a valuable tool for generating protein 3D structures, but its application in structure-based drug design is limited. In this study, we introduce AF Optimizer-a new deep learning-assisted approach that refines binding site geometry b... read more 

BACKGROUND: Although healthy lifestyle behaviours are associated with a lower risk of psoriasis, the underlying metabolic mechanisms remain unclear. OBJECTIVES: To investigate lifestyle-related serum metabolites associated with late-onset psoriasis r... read more 

Polygenic risk scores (PRS) and the prostate specific antigen (PSA) test have been shown to be successful tools for predicting prostate cancer (PCa) incidence. In this study, we assessed the potential of combining PRS and PSA as biomarkers for PCa ag... read more 

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PURPOSE: The Liver Imaging Reporting and Data System (LI-RADS) assessment is subject to inter-reader variability. The present study aimed to evaluate the impact of an artificial intelligence (AI) system on the accuracy and inter-reader agreement of L... read more 

BACKGROUND: The incidence of iatrogenic pharyngeal perforation has been reported to comprise 50%-75% of all pharyngeal perforations. In the context of anterior cervical diskectomy and fusion (ACDF) procedures, pharyngeal perforations are a known, alt... read more 

Objective: This study aimed to evaluate and compare the accuracy, clarity, and clinical applicability of 2 state-of-the-art large language models (LLMs), Chat Generative Pretrained Transformer (ChatGPT)-4o and Grok-3, in generating health information... read more 

Focal cortical dysplasia (FCD) is a neurodevelopmental malformation that often manifests as medically refractory epilepsy. A key histological hallmark of FCD type II is the presence of cytomegalic dysmorphic neurons (CDNs), which are considered to be... read more 

Artificial intelligence (AI) is rapidly emerging as a transformative force in pediatric nephrology, enabling improvements in diagnostic accuracy, therapeutic precision, and operational workflows. By integrating diverse datasets-including patient hist... read more 

Medical imaging plays a crucial role in the accurate diagnosis and prognosis of various medical conditions, with each modality offering unique and complementary insights into the body's structure and function. However, no single imaging technique can... read more