Machine learning-based prediction of vancomycin concentration after abdominal administration in patients with peritoneal dialysis-related peritonitis.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy
PMID: 39034285

Abstract

INTRODUCTION: Peritonitis is a serious complication of peritoneal dialysis (PD), in which insufficient control of antibacterial drug concentrations poses a significant risk for poor outcomes. Predicting antibacterial drug concentrations is crucial in clinical practice. The limitations imposed by compartment models have presented a considerable challenge.

Authors

  • Bo Lv
    Department of Radiation Oncology, Huadong Hospital, Fudan University, Shanghai, China.
  • Wenxiu Liu
    Department of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, China.
  • Ying Lu
    Department of Endocrinology, Institute of Translational Medicine, Health Science Center, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China.
  • Zhi Wang
    Department of Pharmacy, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Aiming Shi
    Department of Pharmacy, The Second Affiliated Hospital of Soochow University, Suzhou, China.

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