Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report.

Journal: Hypertension (Dallas, Tex. : 1979)
Published Date:

Abstract

Hypertension is among the most important risk factors for cardiovascular disease, chronic kidney disease, and dementia. The artificial intelligence (AI) field is advancing quickly, and there has been little discussion on how AI could be leveraged for improving the diagnosis and management of hypertension. AI technologies, including machine learning tools, could alter the way we diagnose and manage hypertension, with potential impacts for improving individual and population health. The development of successful AI tools in public health and health care systems requires diverse types of expertise with collaborative relationships between clinicians, engineers, and data scientists. Unbiased data sources, management, and analyses remain a foundational challenge. From a diagnostic standpoint, machine learning tools may improve the measurement of blood pressure and be useful in the prediction of incident hypertension. To advance the management of hypertension, machine learning tools may be useful to find personalized treatments for patients using analytics to predict response to antihypertension medications and the risk for hypertension-related complications. However, there are real-world implementation challenges to using AI tools in hypertension. Herein, we summarize key findings from a diverse group of stakeholders who participated in a workshop held by the National Heart, Lung, and Blood Institute in March 2023. Workshop participants presented information on communication gaps between clinical medicine, data science, and engineering in health care; novel approaches to estimating BP, hypertension risk, and BP control; and real-world implementation challenges and issues.

Authors

  • Daichi Shimbo
    Department of Medicine, Columbia University Irving Medical Center, New York, NY (D.S., M.A.).
  • Rashmee U Shah
    Division of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City.
  • Marwah Abdalla
    Department of Medicine, Columbia University Irving Medical Center, New York, NY (D.S., M.A.).
  • Ritu Agarwal
    Center for Digital Health and Artificial Intelligence, Johns Hopkins University.
  • Faraz S Ahmad
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
  • Gabriel Anaya
    Division of Cardiovascular Sciences, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, MD (G.A., J.L., Y.S.O., E.I.).
  • Zachi I Attia
    Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
  • Sheana Bull
    Clinic Chat, LLC, 2950 Arkins Ct, Unit 605, Denver, CO, 80216, United States, 1 3038079800.
  • Alexander R Chang
    Departments of Nephrology and Population Health Sciences, Geisinger, Danville, PA (A.R.C.).
  • Yvonne Commodore-Mensah
    Johns Hopkins School of Nursing and Bloomberg School of Public Health, Department of Epidemiology, Baltimore, MD (Y.C.-M.).
  • Keith Ferdinand
    John W. Deming Department of Medicine (K.F.), Tulane University School of Medicine, New Orleans, LA.
  • Kensaku Kawamoto
    Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, USA.
  • Rohan Khera
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Jane Leopold
    Division of Cardiovascular Sciences, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, MD (G.A., J.L., Y.S.O., E.I.).
  • James Luo
    Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (J.L.).
  • Sonya Makhni
    Chicago Medicine, Chicago, IL, USA.
  • Bobak J Mortazavi
    Texas A&M University, USA.
  • Young S Oh
    Division of Cardiovascular Sciences, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, MD (G.A., J.L., Y.S.O., E.I.).
  • Lucia C Savage
    Chief Privacy & Regulatory Officer, Omada Health, Inc, San Francisco, CA (L.C.S.).
  • Erica S Spatz
    Yale University, USA.
  • George Stergiou
    Hypertension Center STRIDE-7, National and Kapodistrian University of Athens, School of Medicine, Third Department of Medicine, Sotiria Hospital, Greece (G.S.).
  • Mintu P Turakhia
    Department of Medicine and Center for Digital Health, Stanford University School of Medicine, Stanford, CA, USA.
  • Paul K Whelton
    Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine (P.K.W.), Tulane University School of Medicine, New Orleans, LA.
  • Clyde W Yancy
    Division of Cardiology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois.
  • Erin Iturriaga
    Division of Cardiovascular Sciences, National Institutes of Health, National Heart, Lung and Blood Institute, Bethesda, MD (G.A., J.L., Y.S.O., E.I.).