AIMC Topic: Hypertension
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Enhanced stroke risk prediction in hypertensive patients through deep learning integration of imaging and clinical data.
BMC medical informatics and decision making
Jul 31, 2025
BACKGROUND: Stroke is one of the leading causes of death and disability worldwide, with a significantly elevated incidence among individuals with hypertension. Conventional risk assessment methods primarily rely on a limited set of clinical parameter...
In silico analysis of atrial fibrillation and hypertension mechanism of action secondary to ibrutinib/acalabrutinib in chronic lymphocytic leukemia.
Scientific reports
Jul 31, 2025
Ibrutinib and acalabrutinib are first- and next-generation Bruton Tyrosine Kinase inhibitors (BTKi), respectively, approved for chronic lymphocytic leukemia (CLL). Ibrutinib has been associated with cardiovascular events, including atrial fibrillatio...
Association between atherogenic index of plasma and hypertension combined with diabetes mellitus in United States adults: an analysis of the NHANES surveys from 2011 to 2016.
Journal of health, population, and nutrition
Jul 30, 2025
INTRODUCTION: Observational studies have indicated that individuals with hypertension (HTN) and diabetes mellitus (DM) tend to exhibit elevated plasma atherogenic index of plasma (AIP), defined as log (triglyceride [TG]/high-density lipoprotein chole...
Candesartan Mitigates Perioperative Neurocognitive Disorders by Modulating Hypertension-Linked Neuroinflammatory Factor.
Neurochemical research
Jul 29, 2025
Perioperative neurocognitive disorders (PND) are linked to neuroinflammation, a key factor in hypertension, but their causal relationship is underexplored. This study aims to investigate whether hypertension is a risk factor for PND, identify related...
Identifying patterns of high intraoperative blood pressure variability in noncardiac surgery using explainable machine learning: a retrospective cohort study.
Annals of medicine
Jul 24, 2025
BACKGROUND: High intraoperative blood pressure variability (HIBPV) is significantly associated with postoperative adverse complications. However, practical tools to characterize perioperative factors associated with HIBPV remain limited. This study a...
Clinical characteristics and CKD care delivery in African American and American Indian or Alaska Native patients: A real-world cohort study.
BMC nephrology
Jul 21, 2025
BACKGROUND: Racially minoritized populations in the United States (US), notably African American (AA) and American Indian/Alaska Native (AI/AN), experience disproportionately higher rates of chronic kidney disease (CKD), diabetes, and hypertension co...
Plasma Metabolomics and Machine Learning Reveals Metabolic Alterations and Diagnostic Biomarkers for Deep Venous Thrombosis in Hypertensive Patients after Traumatic Fracture.
Journal of proteome research
Jul 15, 2025
We aimed to explore the metabolic dysregulations and diagnostic biomarkers for post-traumatic deep venous thrombosis (pt-DVT) in hypertensive (HPT) patients after fracture. An untargeted ultraperformance liquid chromatography-mass spectrometry-based ...
ML enhanced bioactivity prediction for angiotensin II receptor: A potential anti-hypertensive drug target.
Scientific reports
Jul 14, 2025
The process of drug discovery is intricate, and encompasses a series of detailed phases of research, development, and testing, aimed at evaluating the safety and effectiveness of prospective therapeutic agents. Artificial Intelligence has emerged as ...
Unsupervised learning using EHR and census data to identify distinct subphenotypes of newly diagnosed hypertension patients.
PloS one
Jul 9, 2025
BACKGROUND: Hypertension (HTN) is a complex condition with significant heterogeneity in presentation and treatment response. Identifying distinct subphenotypes of HTN may improve our understanding of its underlying mechanisms and guide more precise t...
Network-based machine learning reveals cardiometabolic multimorbidity patterns and modifiable lifestyle factors: a community-focused analysis of NHANES 2015-2018.
BMC public health
Jul 3, 2025
Cardiometabolic Multimorbidity (CMM) has emerged as one of the primary threats to human health globally due to its high incidence, disability, and mortality rates. Accurate identification of CMM patterns is crucial for CMM classification and health m...
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