Prediction of Freezing of Gait in Parkinson's disease based on multi-channel time-series neural network.

Journal: Artificial intelligence in medicine
Published Date:

Abstract

Freezing of Gait (FOG) is a noticeable symptom of Parkinson's disease, like being stuck in place and increasing the risk of falls. The wearable multi-channel sensor system is an efficient method to predict and monitor the FOG, thus warning the wearer to avoid falls and improving the quality of life. However, the existing approaches for the prediction of FOG mainly focus on a single sensor system and cannot handle the interference between multi-channel wearable sensors. Hence, we propose a novel multi-channel time-series neural network (MCT-Net) approach to merge multi-channel gait features into a comprehensive prediction framework, alerting patients to FOG symptoms in advance. Owing to the causal distributed convolution, MCT-Net is a real-time method available to give optimal prediction earlier and implemented in remote devices. Moreover, intra-channel and inter-channel transformers of MCT-Net extract and integrate different sensor position features into a unified deep learning model. Compared with four other state-of-the-art FOG prediction baselines, the proposed MCT-Net obtains 96.21% in accuracy and 80.46% in F1-score on average 2 s before FOG occurrence, demonstrating the superiority of MCT-Net.

Authors

  • Boyan Wang
    Tsinghua University, Beijing, China. Electronic address: wby000000@mail.tsinghua.edu.cn.
  • Xuegang Hu
    Hefei University of Technology, Hefei, China. Electronic address: jsjxhuxg@hfut.edu.cn.
  • Rongjun Ge
    Laboratory of Image Science and Technology, School of Computer Science and Engineering, Southeast University, Nanjing, China; Key Laboratory of Computer Network and Information Integration (Southeast University), Ministry of Education, Nanjing, China; Centre de Recherche en Information Biomedicale Sino-Francais (LIA CRIBs), Rennes, France.
  • Chenchu Xu
    From the Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, 2nd Anzhen Road, Chaoyang District, Beijing, China (N.Z., L.X., Z.F.); Cardiovascular Research Centre, Royal Brompton Hospital, London, England (G.Y., R.S., J.K., D.F.); National Heart and Lung Institute, Imperial College London, London, England (G.Y., R.S., J.K., D.F.); Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China (Z.G., H.Z.); Anhui University, Hefei, China (C.X., Y.Z.); and School of Biomedical Engineering, Sun Yat-Sen University, Shenzhen, China (H.Z.).
  • Jinglin Zhang
    Guangzhou Aier Eye Hospital, Jinan University, Guangzhou, China.
  • Zhifan Gao
    School of Biomedical Engineering, Sun Yat-sen University, Shenzhen, China.
  • Shu Zhao
    Key Laboratory of Intelligent Computing and Signal Processing, Ministry of Education, Anhui University, Hefei, China; School of Computer Science and Technology, Anhui University, Hefei, China.
  • Kemal Polat
    Department of Electrical and Electronics Engineering, Faculty of Engineering, Bolu Abant Izzet Baysal University, Bolu 14280, Turkey.