Validation and depth evaluation of recurrent neural network-based ultra low-pass genome sequencing for the detection of absence of heterozygosity: A multi-centre study of 409 cases.

Abstract

Authors

• Yeqing Qian
  Department of Reproductive Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
• Jianjun Zhu
  Department of Radiology, Zhongda Hospital Southeast University, Nanjing, China.
• Zhiguo Tang
  Andrological Medicine, Maternity and Child Health Hospital of Anhui Province, Affiliated Maternity and Child Health Hospital of Anhui Medical University, Hefei, China.
• Yan Sun
  Department of Biochemistry, Albert Einstein College of Medicine, New York, NY, United States.
• Zhonghua Wang
  Shandong Sport University, Jinan 250102, Shandong, China.
• Fei Tang
  Division of Biostatistics, University of Miami.
• Yun Yang
  Department of Chemistry, South University of Science and Technology, Shenzhen 518055, China.
• Linlin Fan
  Clin Lab, BGI Genomics, Tianjin, 300308, China.
• Yixi Sun
  Department of Reproductive Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
• Bei Liu
  College of Mathematics and Physics, Hunan University of Arts and Science, Changde 415000, China.
• Min Chen
  School of Computer Science and TechnologyHuazhong University of Science and Technology Wuhan 430074 China.
• Yuqin Luo
  Department of Reproductive Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
• Junjie Hu
  Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing 100069, PR China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing 100069, PR China.
• Kai Yan
  Department of Reproductive Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
• Jianfen Man
  Clin Lab, BGI Genomics, Wuhan, 430074, China.
• Lina Wang
  Department of Biochemistry and Molecular Biology, Shandong University School of MedicineJinan, P. R. China; Central Laboratory, The Second Hospital of Shandong UniversityJinan, P. R. China.
• Cangcang Jia
  Clin Lab, BGI Genomics, Wuhan, China.
• Ping Tang
  Aerospace Information Research Institute (AIR), Chinese Academy of Sciences (CAS), Beijing 100101, China. Electronic address: tangping@aircas.ac.cn.
• Xinyi Zhu
  Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China.
• Chaohong Wang
  Medical Genetics Center, Maternity and Child Health Hospital of Anhui Province, Affiliated Maternity and Child Health Hospital of Anhui Medical University, Hefei, China.
• Junxiang Tang
  Medical Genetics Center, Maternity and Child Health Hospital of Anhui Province, Affiliated Maternity and Child Health Hospital of Anhui Medical University, Hefei, China.
• Yuanyuan Xia
  School of Mechanical Engineering, Sichuan University of Science and Engineering, Yibin, China.
• Xueqin Guo
  Clin Lab, BGI Genomics, Wuhan, 430074, China.
• Kang Zhang
  Xifeng District People's Hospital, Qingyang, China.
• Xiaoli Wang
  Demonstration Center of Future Product, Beijing Aircraft Technology Research Institute, COMAC, Beijing, China.
• Suping Li
  Department of Fetal Medical Center, Jiaxing Maternity and Children Health Care Hospital, Jiaxing University, Jiaxing, China.
• Lijie Song
  Clin Lab, BGI Genomics, Tianjin, 300308, China. songlijie@bgi.com.
• Jiansheng Zhu
  Department of Infectious Diseases, Affiliated Taizhou Hospital of Wenzhou Medical University, No.50 Ximeng Road, Taizhou, 317000, China. jianshengzzhu@sina.cn.
• Minyue Dong
  Department of Reproductive Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Keywords

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