AIMC Topic: Loss of Heterozygosity
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Recurrent neural network for predicting absence of heterozygosity from low pass WGS with ultra-low depth.
BMC genomics
May 14, 2024
BACKGROUND: The absence of heterozygosity (AOH) is a kind of genomic change characterized by a long contiguous region of homozygous alleles in a chromosome, which may cause human genetic disorders. However, no method of low-pass whole genome sequenci...
Validation and depth evaluation of recurrent neural network-based ultra low-pass genome sequencing for the detection of absence of heterozygosity: A multi-centre study of 409 cases.
Clinical and translational medicine
Jul 1, 2024
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