Adaptive Multi-Dimensional Weighted Network With Category-Aware Contrastive Learning for Fine-Grained Hand Bone Segmentation.

Journal: IEEE journal of biomedical and health informatics
PMID:

Abstract

Accurately delineating and categorizing individual hand bones in 3D ultrasound (US) is a promising technology for precise digital diagnostic analysis. However, this is a challenging task due to the inherent imaging limitations of the US and the insignificant feature differences among numerous bones. In this study, we have proposed a novel deep learning-based solution for pediatric hand bone segmentation in the US. Our method is unique in that it allows for effective detailed feature mining through an adaptive multi-dimensional weighting attention mechanism. It innovatively implements a category-aware contrastive learning method to highlight inter-class semantic feature differences, thereby enhancing the category discrimination performance of the model. Extensive experiments on the challenging pediatric clinical hand 3D US datasets show the outstanding performance of the proposed method in segmenting thirty-eight bone structures, with the average Dice coefficient of 90.0%. The results outperform other state-of-the-art methods, demonstrating its effectiveness in fine-grained hand bone segmentation. Our method will be globally released as a plugin in the 3D Slicer, providing an innovative and reliable tool for relevant clinical applications.

Authors

  • Bolun Zeng
    Institute of Biomedical Manufacturing and Life Quality Engineering, State Key Laboratory of Mechanical System and Vibration, School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, China.
  • Li Chen
    Department of Endocrinology and Metabolism, Qilu Hospital, Shandong University, Jinan, China.
  • Yuanyi Zheng
    Department of Ultrasound in Medicine, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Ultrasound in Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai, China zhengyuanyi@163.com.
  • Xiaojun Chen
    Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.