Prediction of in-hospital Mortality of Intensive Care Unit Patients with Acute Pancreatitis Based on an Explainable Machine Learning Algorithm.

Journal: Journal of clinical gastroenterology
PMID:

Abstract

BACKGROUND AND AIM: Acute pancreatitis (AP) is potentially fatal. Therefore, early identification of patients at a high mortality risk and timely intervention are essential. This study aimed to establish an explainable machine-learning model for predicting in-hospital mortality of intensive care unit (ICU) patients with AP.

Authors

  • Wensen Ren
    Department of Gastroenterology, the Affiliated Hospital of Southwest Medical University.
  • Kang Zou
    Chinese Evidence-based Medicine Center, Cochrane China Center and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.
  • Shu Huang
    Department of Gastroenterology, the People's Hospital of Lianshui, Huaian, China.
  • Huan Xu
    School of Food Science and Engineering, Hainan University 58 Renmin Avenue Haikou 570228 China zhangzeling@hainanu.edu.cn benchao312@hainanu.edu.cn xuhuan.hnu@foxmail.com qichen@hainanu.edu.cn sunzhichang11@163.com hmcao@hainanu.edu.cn.
  • Wei Zhang
    The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Xiaomin Shi
    Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Street Taiping No.25, Region Jiangyang, Luzhou, Sichuan Province, 646099, China.
  • Lei Shi
  • Xiaolin Zhong
    Department of Gastroenterology, the Affiliated Hospital of Southwest Medical University.
  • Yan Peng
    Key Acu-moxibustion Laboratory of Biological Information Analysis of Institute of Acupuncture, Moxibustion and Massage, Hunan University of Chinese Medicine, Changsha 410007, China.
  • Xiaowei Tang
    Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Street Taiping No.25, Region Jiangyang, Luzhou, Sichuan Province, 646099, China. solitude5834@hotmail.com.
  • Muhan Lü
    Luzhou Key Laboratory of Human Microecology and Precision Diagnosis and Treatment, Luzhou, China.