MCAS-GP: Deep Learning-Empowered Middle Cerebral Artery Segmentation and Gate Proposition.

Journal: IEEE/ACM transactions on computational biology and bioinformatics
Published Date:

Abstract

With the fast development of AI technologies, deep learning is widely applied for biomedical data analytics and digital healthcare. However, there remain gaps between AI-aided diagnosis and real-world healthcare demands. For example, hemodynamic parameters of the middle cerebral artery (MCA) have significant clinical value for diagnosing adverse perinatal results. Nevertheless, the current measurement procedure is tedious for sonographers. To reduce the workload of sonographers, we propose MCAS-GP, a deep learning-empowered framework that tackles the Middle Cerebral Artery Segmentation and Gate Proposition. MCAS-GP can automatically segment the region of the MCA and detect the corresponding position of the gate in the procedure of fetal MCA Doppler assessment. In MCAS-GP, a novel learnable atrous spatial pyramid pooling (LASPP) module is designed to adaptively learn multi-scale features. We also propose a novel evaluation metric, Affiliation Index, for measuring the effectiveness of the position of the output gate. To evaluate our proposed MCAS-GP, we build a large-scale MCA dataset, collaborating with the International Peace Maternity and Child Health Hospital of China welfare institute (IPMCH). Extensive experiments on the MCA dataset and two other public surgical datasets demonstrate that MCAS-GP can achieve considerable performance improvement in both accuracy and inference time.

Authors

  • Rui Zhang
    Department of Cardiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, China.
  • Shuo Wang
    College of Tea & Food Science, Anhui Agricultural University, Hefei, China.
  • Ruhui Ma
  • Yang Hua
    Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
  • Tao Song
    Department of Cleft Lip and Palate, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing.
  • Yunyun Cao
  • Haibing Guan