Estimating the dim light melatonin onset of adolescents within a 6-h sampling window: the impact of sampling rate and threshold method.

Journal: Sleep medicine
Published Date: Dec 18, 2015

Abstract

OBJECTIVE/BACKGROUND: Circadian rhythm sleep-wake disorders (CRSWDs) often manifest during the adolescent years. Measurement of circadian phase such as the dim light melatonin onset (DLMO) improves diagnosis and treatment of these disorders, but financial and time costs limit the use of DLMO phase assessments in clinic. The current analysis aims to inform a cost-effective and efficient protocol to measure the DLMO in older adolescents by reducing the number of samples and total sampling duration.

Authors

  • Stephanie J Crowley
    Biological Rhythms Research Laboratory, Department of Behavioral Sciences, Rush University Medical Center, 1645 W. Jackson Blvd, Chicago, IL 60612, USA. Electronic address: stephanie_j_crowley@rush.edu.
  • Christina Suh
    Biological Rhythms Research Laboratory, Department of Behavioral Sciences, Rush University Medical Center, 1645 W. Jackson Blvd, Chicago, IL 60612, USA.
  • Thomas A Molina
    Biological Rhythms Research Laboratory, Department of Behavioral Sciences, Rush University Medical Center, 1645 W. Jackson Blvd, Chicago, IL 60612, USA.
  • Louis F Fogg
    Community Systems and Mental Health Nursing, Rush University Medical Center, 1653 W. Congress Parkway, Chicago, IL 60612, USA.
  • Katherine M Sharkey
    Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, University Medicine, Rhode Island Hospital, and Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI, USA; Sleep for Science Research Laboratory, Department of Psychiatry & Human Behavior, Alpert Medical School of Brown University, 300 Duncan Drive, Providence, RI 02906, USA.
  • Mary A Carskadon
    Sleep for Science Research Laboratory, Department of Psychiatry & Human Behavior, Alpert Medical School of Brown University, 300 Duncan Drive, Providence, RI 02906, USA; Centre for Sleep Research, University of South Australia, GPO Box 2471, Adelaide, South Australia 5001, Australia.

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