The Dawn of a New Pharmaceutical Epoch: Can AI and Robotics Reshape Drug Formulation?

Journal: Advanced healthcare materials
Published Date: Aug 18, 2024

Abstract

Over the last four decades, pharmaceutical companies' expenditures on research and development have increased 51-fold. During this same time, clinical success rates for new drugs have remained unchanged at about 10 percent, predominantly due to lack of efficacy and/or safety concerns. This persistent problem underscores the need to innovate across the entire drug development process, particularly in drug formulation, which is often deprioritized and under-resourced.

Authors

  • Pauric Bannigan
  • Riley J Hickman
    Chemical Physics Theory Group, Department of Chemistry, University of Toronto, Toronto, Canada.
  • Alán Aspuru-Guzik
    Departments of Chemistry, Computer Science, University of Toronto St. George Campus Toronto ON Canada.
  • Christine Allen

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