Recent advances in artificial intelligence (AI) and machine learning (ML) are revolutionizing nanopharmaceutical development by enabling data-driven formulation design, process optimization, and prediction of biological performance. AI encompasses co...
European journal of hospital pharmacy : science and practice
Dec 23, 2025
OBJECTIVE: This study aims to evaluate the risk of occupational exposure to hazardous medicinal products (HMPs) when utilising robotic compounding systems for the preparation of antineoplastic sterile medications. Specifically, it assesses the levels...
Lipid nanoparticles (LNPs) have gained significant attention thanks to their ability to encapsulate and deliver mRNA. Exploring a variety of lipid compositions and different preparation processes is essential for a better understanding of the mRNA en...
Efficient determination of developable protein drug candidates and stable solution conditions is a key challenge in industrial drug development. Protein aggregation is difficult to predict and can lead to challenges in manufacturing, storage, and pat...
International journal of pharmaceutics
Dec 8, 2025
Driven by the Food and Drug Administration's Quality-by-Design initiative and the advancements of Industry 4.0, the pharmaceutical industry is transitioning from traditional batch manufacturing to advanced manufacturing. This transition requires resh...
Since Pfizer developed the mRNA vaccine for COVID-19 by leveraging artificial intelligence (AI) for designing the vaccine, integrating AI and allied domains in the drug development process has escalated at an unimaginable rate. Owing to the complex a...
International journal of pharmaceutics
Nov 25, 2025
Defining suspension stability can be extremely complex, but beyond critical during the formulation development of nano- and microsuspensions intended for long-acting injectables. As of now, the current practice is based on the trial-and-error approac...
International journal of pharmaceutics
Nov 24, 2025
Over the past two decades, a diverse array of ultrasonic and acoustic elastic-wave techniques has been developed to non-destructively assess macro- and micro-scale properties of compressed Oral Solid Dosage (OSD) forms. These methods are increasingly...
International journal of pharmaceutics
Nov 16, 2025
Pharmaceutical 3D printing is an emerging digital manufacturing technology capable of autonomously producing personalised medicines. However, the same reliance on digital workflows that enables this innovation also introduces new vulnerabilities, mos...
International journal of pharmaceutics
Nov 4, 2025
Liposomes have transformed drug delivery by enhancing the solubility, stability, and bioavailability of therapeutic agents, driving widespread clinical adoption and contributing to a rapidly expanding multi-billion-dollar market. However, despite the...
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