Could machine learning revolutionize how we treat immune thrombocytopenia?

Journal: British journal of haematology
PMID:

Abstract

The absence of reliable biomarkers in immune thrombocytopenia (ITP) complicates treatment choice, necessitating a trial-and-error approach. Machine learning (ML) holds promise for transforming ITP treatment by analysing complex data to identify predictive factors, as demonstrated by Xu et al.'s study which developed ML-based models to predict responses to corticosteroids, rituximab and thrombopoietin receptor agonists. However, these models require external validation before can be adopted in clinical practice. Commentary on: Xu et al. A novel scoring model for predicting efficacy and guiding individualised treatment in immune thrombocytopenia. Br J Haematol 2024; 205:1108-1120.

Authors

  • Waleed Ghanima
    Department of Research, Norway and Institute of Clinical Medicine, Østfold Hospital, University of Oslo, Oslo, Norway.
  • Nichola Cooper
    Department of Immunology and Inflammation, Imperial College, London, UK.