Age prediction from 12-lead electrocardiograms using deep learning: a comparison of four models on a contemporary, freely available dataset.

Journal: Physiological measurement
Published Date:

Abstract

The 12-lead electrocardiogram (ECG) is routine in clinical use and deep learning approaches have been shown to have the identify features not immediately apparent to human interpreters including age and sex. Several models have been published but no direct comparisons exist.We implemented three previously published models and one unpublished model to predict age and sex from a 12-lead ECG and then compared their performance on an open-access data set.All models converged and were evaluated on the holdout set. The best preforming age prediction model had a hold-out set mean absolute error of 8.06 years. The best preforming sex prediction model had a hold-out set area under the receiver operating curve of 0.92.We compared performance of four models on an open-access dataset.

Authors

  • Andrew Barros
    Center for Advanced Medical Analytics (CAMA), School of Medicine, University of Virginia, Charlottesville, VA, United States of America.
  • Ian German Mesner
    Center for Advanced Medical Analytics (CAMA), School of Medicine, University of Virginia, Charlottesville, VA, United States of America.
  • N Rich Nguyen
    Center for Advanced Medical Analytics (CAMA), School of Medicine, University of Virginia, Charlottesville, VA, United States of America.
  • J Randall Moorman
    University of Virginia School of Medicine, Department of Internal Medicine, Division of Cardiovascular Diseases, Charlottesville, VA, USA; University of Virginia Center for Advanced Medical Analytics, Charlottesville, VA, USA. Electronic address: rm3h@virginia.edu.