Promoting smartphone-based keratitis screening using meta-learning: A multicenter study.

Journal: Journal of biomedical informatics
PMID:

Abstract

OBJECTIVE: Keratitis is the primary cause of corneal blindness worldwide. Prompt identification and referral of patients with keratitis are fundamental measures to improve patient prognosis. Although deep learning can assist ophthalmologists in automatically detecting keratitis through a slit lamp camera, remote and underserved areas often lack this professional equipment. Smartphones, a widely available device, have recently been found to have potential in keratitis screening. However, given the limited data available from smartphones, employing traditional deep learning algorithms to construct a robust intelligent system presents a significant challenge. This study aimed to propose a meta-learning framework, cosine nearest centroid-based metric learning (CNCML), for developing a smartphone-based keratitis screening model in the case of insufficient smartphone data by leveraging the prior knowledge acquired from slit-lamp photographs.

Authors

  • Zhongwen Li
    Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, China.
  • Yangyang Wang
  • Kuan Chen
    Infervision, Beijing, China.
  • Wei Qiang
    Ningbo Eye Hospital, Wenzhou Medical University, Ningbo 315000, China.
  • Xihang Zong
    Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo 315040, China.
  • Ke Ding
    Intel Corporation, United States of America.
  • Shihong Wang
    Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo 315040, China.
  • Shiqi Yin
    Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo 315040, China.
  • Jiewei Jiang
    School of Computer Science and Technology, Xidian University, No. 2 South Taibai Rd, Xi'an, 710071, China.
  • Wei Chen
    Department of Urology, Zigong Fourth People's Hospital, Sichuan, China.