Predicting Progression to Dementia Using Auditory Verbal Learning Test in Community-Dwelling Older Adults Based On Machine Learning.

Journal: The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
PMID: 39645504

Abstract

BACKGROUND: Primary healthcare institutions find identifying individuals with dementia particularly challenging. This study aimed to develop machine learning models for identifying predictive features of older adults with normal cognition to develop dementia.

Authors

  • Xin-Yan Xie
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan; Geriatric Hospital Affiliated to Wuhan University of Science and Technology (XYX, DL, GRC, FFH, LX, YMO, XXC, YLZ, JQL, QW, YFM, WT, YZ), Wuhan; School of Public Health (XYX, DL, LX, YMO, YSC, JQL, ZW, YZ), Wuhan University of Science and Technology, Wuhan.
  • Lin-Ya Huang
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan.
  • Dan Liu
    Department of Bioengineering, Temple University, Philadelphia, PA, United States.
  • Gui-Rong Cheng
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan; Geriatric Hospital Affiliated to Wuhan University of Science and Technology (XYX, DL, GRC, FFH, LX, YMO, XXC, YLZ, JQL, QW, YFM, WT, YZ), Wuhan; School of Public Health (XYX, DL, LX, YMO, YSC, JQL, ZW, YZ), Wuhan University of Science and Technology, Wuhan.
  • Fei-Fei Hu
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan; Geriatric Hospital Affiliated to Wuhan University of Science and Technology (XYX, DL, GRC, FFH, LX, YMO, XXC, YLZ, JQL, QW, YFM, WT, YZ), Wuhan; School of Public Health (XYX, DL, LX, YMO, YSC, JQL, ZW, YZ), Wuhan University of Science and Technology, Wuhan.
  • Juan Zhou
    Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
  • Jing-Jing Zhang
    Department of Environmental Health and Occupational Medicine,West China School of Public Health,Sichuan University,Chengdu 610041,China.
  • Gang-Bin Han
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan.
  • Jing-Wen Geng
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan.
  • Xiao-Chang Liu
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan.
  • Jun-Yi Wang
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan.
  • De-Yang Zeng
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan.
  • Jing Liu
    Department of Ophthalmology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Qian-Qian Nie
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan.
  • Dan Song
    Department of Ophthalmology, Beijing Tisnghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
  • Shi-Yue Li
    State Key Laboratory of Respiratory Diseases, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China lishiyue@188.com.
  • Cheng Cai
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan.
  • Yu-Yang Cui
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan.
  • Lang Xu
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan; Geriatric Hospital Affiliated to Wuhan University of Science and Technology (XYX, DL, GRC, FFH, LX, YMO, XXC, YLZ, JQL, QW, YFM, WT, YZ), Wuhan; School of Public Health (XYX, DL, LX, YMO, YSC, JQL, ZW, YZ), Wuhan University of Science and Technology, Wuhan.
  • Yang-Ming Ou
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan; Geriatric Hospital Affiliated to Wuhan University of Science and Technology (XYX, DL, GRC, FFH, LX, YMO, XXC, YLZ, JQL, QW, YFM, WT, YZ), Wuhan; School of Public Health (XYX, DL, LX, YMO, YSC, JQL, ZW, YZ), Wuhan University of Science and Technology, Wuhan.
  • Xing-Xing Chen
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan; Geriatric Hospital Affiliated to Wuhan University of Science and Technology (XYX, DL, GRC, FFH, LX, YMO, XXC, YLZ, JQL, QW, YFM, WT, YZ), Wuhan; School of Public Health (XYX, DL, LX, YMO, YSC, JQL, ZW, YZ), Wuhan University of Science and Technology, Wuhan.
  • Yan-Ling Zhou
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan; Geriatric Hospital Affiliated to Wuhan University of Science and Technology (XYX, DL, GRC, FFH, LX, YMO, XXC, YLZ, JQL, QW, YFM, WT, YZ), Wuhan.
  • Yu-Shan Chen
    West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, China.
  • Jin-Quan Li
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan; Geriatric Hospital Affiliated to Wuhan University of Science and Technology (XYX, DL, GRC, FFH, LX, YMO, XXC, YLZ, JQL, QW, YFM, WT, YZ), Wuhan; School of Public Health (XYX, DL, LX, YMO, YSC, JQL, ZW, YZ), Wuhan University of Science and Technology, Wuhan.
  • Zhen Wei
    Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu 215123, China.
  • Qiong Wu
    Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing 211816, P. R. China.
  • Yu-Fei Mei
    Hubei Provincial Clinical Research Center for Alzheimer's Disease (XYX, LYH, DL, GRC, FFH, JZ, JJZ, GBH, JWG, XCL, JYW, DYZ, JL, QQN, DS, SYL, CC, YYC, LX, YMO, XXC, YLZ, YSC, JQL, ZW, QW, YFM, YZ), Tian You Hospital Affiliated to Wuhan University of Science and Technology, Wuhan; Geriatric Hospital Affiliated to Wuhan University of Science and Technology (XYX, DL, GRC, FFH, LX, YMO, XXC, YLZ, JQL, QW, YFM, WT, YZ), Wuhan; School of Public Health (XYX, DL, LX, YMO, YSC, JQL, ZW, YZ), Wuhan University of Science and Technology, Wuhan.
  • Shao-Jun Song
    Reproductive Medicine Center (SJS), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan.
  • Wei Tan
    Weifang People's Hospital, Guang Wen Road, Weifang 261000, China.
  • Qian-Hua Zhao
    Department of Neurology (QHZ, DD), Huashan Hospital, Fudan University, Shanghai; National Center for Neurological Disorders (QHZ, DD), Huashan Hospital, Fudan University, Shanghai; National Clinical Research Center for Aging and Medicine (QHZ, DD), Huashan Hospital, Fudan University, Shanghai.
  • Ding Ding
    College of Foreign Languages, Shangqiu Normal University, Shangqiu, Henan 476000, China.
  • Yan Zeng
    Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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