Machine learning-based forecast of Helmet-CPAP therapy failure in Acute Respiratory Distress Syndrome patients.

Journal: Computer methods and programs in biomedicine
PMID:

Abstract

BACKGROUND AND OBJECTIVE: Helmet-Continuous Positive Airway Pressure (H-CPAP) is a non-invasive respiratory support that is used for the treatment of Acute Respiratory Distress Syndrome (ARDS), a severe medical condition diagnosed when symptoms like profound hypoxemia, pulmonary opacities on radiography, or unexplained respiratory failure are present. It can be classified as mild, moderate or severe. H-CPAP therapy is recommended as the initial treatment approach for mild ARDS. Even though the efficacy of H-CPAP in managing patients with moderate-to-severe hypoxemia remains unclear, its use has increased for these cases in response to the emergence of the COVID-19 Pandemic. Using the electronic medical records (EMR) from the Pulmonology Department of Vimercate Hospital, in this study we develop and evaluate a Machine Learning (ML) system able to predict the failure of H-CPAP therapy on ARDS patients.

Authors

  • Riccardo Campi
    Department of Urology, University of Florence, Careggi Hospital, Florence, Italy. Electronic address: riccardo.campi@unifi.it.
  • Antonio De Santis
    Politecnico di Milano, Dipartimento di Elettronica, Informazione e Bioingegneria, Piazza Leonardo Da Vinci 32, Milano, MI, 20133, Italy. Electronic address: antonio.desantis@polimi.it.
  • Paolo Colombo
    Azienda Socio Sanitaria Territoriale della Brianza, Via Santi Cosma e Damiano 10, Vimercate, MB, 20871, Italy. Electronic address: paolo.colombo@asst-brianza.it.
  • Paolo Scarpazza
    Azienda Socio Sanitaria Territoriale della Brianza, Via Santi Cosma e Damiano 10, Vimercate, MB, 20871, Italy. Electronic address: paolo.scarpazza@asst-brianza.it.
  • Marco Masseroli