Artificial intelligence in the care of children and adolescents with chronic diseases: a systematic review.

Journal: European journal of pediatrics
PMID:

Abstract

UNLABELLED: The integration of artificial intelligence (AI) and machine learning (ML) has shown potential for various applications in the medical field, particularly for diagnosing and managing chronic diseases among children and adolescents. This systematic review aims to comprehensively analyze and synthesize research on the use of AI for monitoring, guiding, and assisting pediatric patients with chronic diseases. Five major electronic databases were searched (Medline, Scopus, PsycINFO, ACM, Web of Science), along with manual searches of gray literature, personal archives, and reference lists of relevant papers. All original studies as well as conference abstracts and proceedings, focusing on AI applications for pediatric chronic disease care were included. Thirty-one studies met the inclusion criteria. We extracted AI method used, study design, population, intervention, and main results. Two researchers independently extracted data and resolved discrepancies through discussion. AI applications are diverse, encompassing, e.g., disease classification, outcome prediction, or decision support. AI generally performed well, though most models were tested on retrospective data. AI-based tools have shown promise in mental health analysis, e.g., by using speech sampling or social media data to predict therapy outcomes for various chronic conditions.

Authors

  • Janna-Lina Kerth
    Dept. of General Pediatrics, Pediatric Cardiology and Neonatology, Medical Faculty, University Children's Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, 40227, Düsseldorf, Germany. janna-lina.kerth@med.uni-duesseldorf.de.
  • Maurus Hagemeister
    Dept. of General Pediatrics, Pediatric Cardiology and Neonatology, Medical Faculty, University Children's Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, 40227, Düsseldorf, Germany.
  • Anne C Bischops
    Dept. of General Pediatrics, Pediatric Cardiology and Neonatology, Medical Faculty, University Children's Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, 40227, Düsseldorf, Germany.
  • Lisa Reinhart
    Dept. of General Pediatrics, Pediatric Cardiology and Neonatology, Medical Faculty, University Children's Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, 40227, Düsseldorf, Germany.
  • Juergen Dukart
    F. Hoffmann-La Roche, pRED, Pharma Research and Early Development, DTA Neuroscience, Basel, Switzerland.
  • Bert Heinrichs
    Institute of Neurosciences and Medicine, Ethics in the Neurosciences (INM-8), Research Center Jülich, Jülich, Germany.
  • Simon B Eickhoff
    Institute of Neuroscience and Medicine (INM-1, INM-3), Research Centre Jülich, Jülich, Germany.
  • Thomas Meissner
    Dept. of General Pediatrics, Pediatric Cardiology and Neonatology, Medical Faculty, University Children's Hospital Düsseldorf, Heinrich Heine University, Moorenstr. 5, 40227, Düsseldorf, Germany.