AIMC Topic: Chronic Disease

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MRI-derived quantification of hepatic vessel-to-volume ratios in chronic liver disease using a deep learning approach.

European radiology experimental
BACKGROUND: We aimed to quantify hepatic vessel volumes across chronic liver disease stages and healthy controls using deep learning-based magnetic resonance imaging (MRI) analysis, and assess correlations with biomarkers for liver (dys)function and ...

Developing an AI-powered wound assessment tool: a methodological approach to data collection and model optimization.

BMC medical informatics and decision making
BACKGROUND: Chronic wounds (CWs) represent a significant and growing challenge in healthcare due to their prolonged healing times, complex management, and associated costs. Inadequate wound assessment by healthcare professionals (HCPs), often due to ...

High-intensity interval training with robot-assisted gait therapy vs. treadmill gait therapy in chronic stroke: a randomized controlled trial.

Journal of neuroengineering and rehabilitation
OBJECTIVE: Stroke is a leading cause of long-term disability, significantly impacting patients' mobility and quality of life. Robot-assisted gait therapy (RAGT) and high-intensity interval training (HIIT) have individually shown potential in improvin...

Type of pre-existing chronic conditions and their associations with Merkel cell carcinoma (MCC) treatment: Prediction and interpretation using machine learning methods.

PloS one
OBJECTIVE: This study examined the prevalence of pre-existing chronic conditions and their association with the receipt of specific cancer-directed treatments among older adults with incident primary Merkel Cell Carcinoma (MCC) using novel predictive...

The association of life's essential 8 with prevalence of chronic respiratory diseases in adults: insights from NHANES 2007-2018.

BMC pulmonary medicine
OBJECTIVE: Chronic respiratory diseases (CRDs) and cardiovascular diseases (CVD) share common risk factors and frequently co-occur, leading to poorer outcomes. Life's Essential 8 (LE8), a novel metric for cardiovascular health, may provide insights i...

Multidomain Behavioral Change Digital Coaching for Chronic Disease Management in Patients With Type 2 Diabetes: Framework Development and Preliminary Evaluation.

JMIR formative research
BACKGROUND: Unhealthy lifestyle behaviors have been identified as a major cause of numerous health issues, with a steady global increase in their prevalence. Addressing this challenge requires comprehensive behavioral changes to promote the adoption ...

Enhancing chronic wound assessment through agreement analysis and tissue segmentation.

Scientific reports
Accurate monitoring of chronic wound progression is crucial for assessing healing dynamics. However, the current manual process of tissue segmentation and quantification, which is an indicator of the healing progress, is time-consuming and subject to...

Machine learning based gut microbiota pattern and response to fiber as a diagnostic tool for chronic inflammatory diseases.

BMC microbiology
Gut microbiota has been implicated in the pathogenesis of multiple gastrointestinal (GI) and systemic metabolic and inflammatory disorders where disrupted gut microbiota composition and function (dysbiosis) has been found in multiple studies. Thus, h...

Immuno-transcriptomic analysis based on machine learning identifies immunity signature genes of chronic rhinosinusitis with nasal polyps.

Scientific reports
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a prevalent inflammatory disease where immunomodulation plays a pivotal role. However, immuno-transcriptomic characteristics and its clinical relevance remains largely known. We analyzed transcript...

The two ends of the spectrum: comparing chronic schizophrenia and premorbid latent schizotypy by actigraphy.

BMC psychiatry
Motor activity alterations are key symptoms of psychiatric disorders like schizophrenia. Actigraphy, a non-invasive monitoring method, shows promise in early identification. This study characterizes Positive Schizotypy Factor (PSF) and Chronic Schizo...