Artificial intelligence applied in identifying left ventricular walls in myocardial perfusion scintigraphy images: Pilot study.

Journal: PloS one
PMID:

Abstract

This paper proposes the use of artificial intelligence techniques, specifically the nnU-Net convolutional neural network, to improve the identification of left ventricular walls in images of myocardial perfusion scintigraphy, with the objective of improving the diagnosis and treatment of coronary artery disease. The methodology included data collection in a clinical environment, followed by data preparation and analysis using the 3D Slicer Platform for manual segmentation, and subsequently, the application of artificial intelligence models for automated segmentation, focusing on the efficiency of identifying the walls of the left ventricular. A total of 83 clinical routine exams were collected, each exam containing 50 slices, which is 4,150 images. The results demonstrate the efficiency of the proposed artificial intelligence model, with a Dice coefficient of 87% and an average Intersection over Union of 0.8, reflecting high agreement with the manual segmentations produced by experts and surpassing traditional interpretation methods. The internal and external validation of the model corroborates its future applicability in real clinical scenarios, offering a new perspective in the analysis of myocardial perfusion scintigraphy images. The integration of artificial intelligence into the process of analyzing myocardial perfusion scintigraphy images represents a significant advancement in diagnostic accuracy, promoting substantial improvements in the interpretation of medical images, and establishing a foundation for future research and clinical applications, such as artifact correction.

Authors

  • Solange Amorim Nogueira
    Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
  • Fernanda Ambrogi B Luz
    Electrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.
  • Thiago Fellipe O Camargo
    Electrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.
  • Julio Cesar S Oliveira
    Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
  • Guilherme Carvalho Campos Neto
    Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
  • Felipe Brazao F Carvalhaes
    Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
  • Marcio Rodrigues C Reis
    Electrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.
  • Paulo Victor Santos
    Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
  • Giovanna Souza Mendes
    Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
  • Rafael Maffei Loureiro
    Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
  • Daniel Tornieri
    Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
  • Viviane M Gomes Pacheco
    Electrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.
  • Antonio Paulo Coimbra
    Systems and Robotics Institute, Coimbra University, Coimbra, Portugal.
  • Wesley Pacheco Calixto
    Electrical, Mechanical & Computer Engineering School, Federal University of Goias, Goiania, Brazil.