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Coronary Artery Disease

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[Coronary computed tomography in the clinical arena. Recent evidence and future perspectives].

Giornale italiano di cardiologia (2006)
In the past few years, computed tomography coronary angiography (CTCA) has rapidly become a widely used diagnostic tool in several clinical settings and is recommended by the European guidelines with a high degree of recommendation in patients with s...

Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxic foam cell-transformed smooth muscle cells.

Journal of translational medicine
BACKGROUND: Vascular smooth muscle cells loaded with cholesterol (foam-VSMCs) play a crucial role in the progression of human atherosclerosis. Exchange Protein Directly Activated by cAMP 1 (EPAC1) is a critical protein in the regulation of vascular t...

Deep Learning-based Quantitative CT Myocardial Perfusion Imaging and Risk Stratification of Coronary Artery Disease.

Radiology
Background Precise assessment of myocardial ischemia burden and cardiovascular risk stratification based on dynamic CT myocardial perfusion imaging (MPI) is lacking. Purpose To develop and validate a deep learning (DL) model for automated quantificat...

Optimising coronary imaging decisions with machine learning: an external validation study.

Open heart
BACKGROUND: Exclusion of coronary stenosis in individuals with suggestive symptoms is challenging. Cardiac CT or coronary angiography is often used but is inefficient and costly and involves risks. Sex-stratified algorithms based on electronic health...

Comparison of machine learning models with conventional statistical methods for prediction of percutaneous coronary intervention outcomes: a systematic review and meta-analysis.

BMC cardiovascular disorders
INTRODUCTION: Percutaneous coronary intervention (PCI) has been the main treatment of coronary artery disease (CAD). In this review, we aimed to compare the performance of machine learning (ML) vs. logistic regression (LR) models in predicting differ...

Coronary artery disease severity and location detection using deep-mining-based magnetocardiography pattern features.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: The objective of this study was to develop an automated, accurate method of assessing coronary artery disease (CAD), including its severity and location, using deep-mining-based magnetocardiography (MCG) pattern features.

Portable ECG and PCG wireless acquisition system and multiscale CNN feature fusion Bi-LSTM network for coronary artery disease diagnosis.

Computers in biology and medicine
Coronary artery disease (CAD) is a major cause of mortality, especially among aging populations, making timely and accurate diagnosis essential. In this work, a portable wireless device powered by artificial intelligence for CAD detection is proposed...

Diagnostic Accuracy of On-Premise Automated Coronary CT Angiography Analysis Based on Coronary Artery Disease Reporting and Data System 2.0.

Radiology
Background Chest pain is a leading cause of outpatient and emergency department visits; advancements in artificial intelligence (AI) could improve coronary CT angiography (CCTA) workflows for these patients. Purpose To evaluate the performance of an ...

Identification of hub biomarkers in coronary artery disease patients using machine learning and bioinformatic analyses.

Scientific reports
Understanding the molecular underpinnings of CAD is essential for developing effective therapeutic strategies. This study aims to identify and analyze differentially expressed hub biomarkers in the peripheral blood of CAD patients. Based on RNA-seq d...