AIMC Topic: Coronary Artery Disease

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Lesion stratification with intracoronary imaging.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Intracoronary (IC) imaging-guided percutaneous coronary intervention (PCI) improves clinical outcomes in patients with high clinical and anatomical risk when compared to interventions guided by angiography alone. Recent Class I recommendations for th...

Differences in different reconstruction algorithms for coronary CTA demonstrating pericoronary adipose tissue attenuation.

Scientific reports
The Fat Attenuation Index (FAI) surrounding the coronary arteries, a sensitive biomarker for coronary inflammation, can be measured through standard Coronary Computed Tomography Angiography (CCTA). The aim of this study is to evaluate the differences...

AI-driven tongue image analysis for diagnosing and predicting coronary artery disease.

Scientific reports
Coronary artery disease is a leading cause of mortality worldwide, with current diagnostic methods presenting challenges of invasiveness and accuracy. This study investigates artificial intelligence-powered tongue image analysis as a novel, non-invas...

Interpretable and reproducible machine learning model for coronary calcification and segment-level stenoses stratification on computed tomography angiography.

BMC medicine
BACKGROUND: Coronary computed tomography angiography (CCTA) is widely used as a first-line tool for diagnosing and managing coronary artery disease (CAD), and machine learning (ML)-based analysis shows promise for quantitative CAD assessment.

Plasma metabolomics disentangles T2DM- and CAD-specific dysmetabolism and identifies potential biomarkers for CAD risk escalation in diabetic patients.

Cardiovascular diabetology
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a major driver of coronary artery disease (CAD). Prior studies often conflate T2DM- and CAD-specific metabolic alterations, limiting insights into CAD pathogenesis in T2DM. This study aimed to distinguis...

Distinct immune-metabolic phenotypes underlie poor coronary collateral circulation.

Cardiovascular diabetology
BACKGROUND: Coronary collateral circulation (CCC) significantly impacts myocardial perfusion and clinical outcomes in coronary artery disease patients, yet the underlying molecular heterogeneity remains inadequately characterized.

C-reactive protein-triglyceride glucose index in predicting three-vessel coronary artery disease risk: a retrospective study using machine learning approaches.

Annals of medicine
BACKGROUND: Three-vessel coronary artery disease (TVD) is a severe subtype of coronary heart disease, strongly associated with inflammation and metabolic dysfunction. The C-reactive protein-triglyceride glucose index (CTI), an integrated measure of i...

State of the Art: Evaluation and Medical Management of Nonobstructive Coronary Artery Disease in Patients With Chest Pain: A Scientific Statement From the American Heart Association.

Circulation
Risk stratification of patients with chest pain has traditionally focused on identifying obstructive coronary artery disease (CAD). Using this traditional approach, many symptomatic individuals are found to have nonobstructive CAD. The 2021 American ...