Derivation and validation of a clinical predictive model for longer duration diarrhea among pediatric patients in Kenya using machine learning algorithms.

Journal: BMC medical informatics and decision making
PMID:

Abstract

BACKGROUND: Despite the adverse health outcomes associated with longer duration diarrhea (LDD), there are currently no clinical decision tools for timely identification and better management of children with increased risk. This study utilizes machine learning (ML) to derive and validate a predictive model for LDD among children presenting with diarrhea to health facilities.

Authors

  • Billy Ogwel
    Kenya Medical Research Institute, Center for Global Health Research (KEMRI-CGHR) Kisumu Kenya.
  • Vincent H Mzazi
    Department of Information Systems, University of South Africa, Pretoria, South Africa.
  • Alex O Awuor
    Kenya Medical Research Institute- Center for Global Health Research (KEMRI-CGHR), P.O Box 1578-40100, Kisumu, Kenya.
  • Caleb Okonji
    Kenya Medical Research Institute- Center for Global Health Research (KEMRI-CGHR), P.O Box 1578-40100, Kisumu, Kenya.
  • Raphael O Anyango
    Kenya Medical Research Institute- Center for Global Health Research (KEMRI-CGHR), P.O Box 1578-40100, Kisumu, Kenya.
  • Caren Oreso
    Kenya Medical Research Institute- Center for Global Health Research (KEMRI-CGHR), P.O Box 1578-40100, Kisumu, Kenya.
  • John B Ochieng
    Kenya Medical Research Institute- Center for Global Health Research (KEMRI-CGHR), P.O Box 1578-40100, Kisumu, Kenya.
  • Stephen Munga
    Kenya Medical Research Institute- Center for Global Health Research (KEMRI-CGHR), P.O Box 1578-40100, Kisumu, Kenya.
  • Dilruba Nasrin
    Department of Medicine, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Kirkby D Tickell
    Department of Global Health, University of Washington, Seattle, USA.
  • Patricia B Pavlinac
    Department of Global Health, University of Washington, Seattle, USA.
  • Karen L Kotloff
    Center for Vaccine Development, Departments of Pediatrics and Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: KKOTLOFF@medicine.umaryland.edu.
  • Richard Omore
    Kenya Medical Research Institute, Center for Global Health Research (KEMRI-CGHR) Kisumu Kenya.