Beyond the hot flashes: how machine learning is uncovering the complexity of menopause-related depression.

Journal: CNS spectrums
PMID: 39757448

Abstract

BACKGROUND: The transition into menopause marks a significant stage in a woman's life, indicating the end of reproductive capability. This period, encompassing perimenopause and menopause, is characterized by declining levels of estrogen and progesterone, leading to various symptoms such as hot flashes, sleep disturbances, sexual dysfunction, and mood irregularities. Moreover, cognitive functions, notably memory, may decline during this phase.

Authors

  • Graziella Orrù
    Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
  • Rebecca Ciacchini
    Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
  • Anna Conversano
    Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
  • Ciro Conversano
    Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.
  • Angelo Gemignani
    Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy.

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