Loneliness is a major psychological challenge in older adulthood, contributing to increased risks of depression, anxiety, and mortality. Conversational agents - technologies that interact with users via natural language - have emerged as potential to...
BACKGROUND: The evolution of language models, particularly large language models, has introduced transformative potential for psychological assessment, challenging traditional rating scale methods that have dominated clinical practice for over a cent...
Journal of physiological anthropology
Dec 24, 2025
OBJECTIVE: Depression manifests significant emotional dysregulation, characterized by heightened sadness susceptibility and attenuated happiness responsiveness in individuals with depression (IWD). This study employs structured emotion induction prot...
Good mental health is crucial for well-being. Unfortunately, despite the advancements of automatic detection solutions in the mental health field, along with the existence of effective treatments, a large percentage of affected people receive no care...
BACKGROUND: Large language models (LLMs) have rapidly advanced across numerous fields, including mental health care. A shortage of trained therapists and mental health care providers has driven informal use of LLMs for therapeutic support. However, t...
Non-Suicidal Self-Injury (NSSI) is a prevalent and complex behavior among adolescents, often linked to negative emotions such as loneliness, anxiety, and emptiness. Traditional self-report and experimental methods rely on autobiographical recall and ...
Mental health disorders, such as depression and anxiety, are increasing, and thus, there is a necessity for accurate and effective detection. K-Nearest Neighbors (KNN) and extensions have been extensively used in disease detection. In this work, Adap...
Therapeutic options for refractory depression are urgently needed. We conducted a deep brain stimulation (DBS) randomized controlled trial of the bed nucleus of the stria terminalis (BNST), an extended amygdala structure, and nucleus accumbens (NAc) ...
BMC medical informatics and decision making
Nov 6, 2025
BACKGROUND: Adolescent depression is a major public health concern. Physical health indicators are rarely included in risk tools. We examined whether adding dry eye disease (DED) to psychosocial and behavioral factors improves prediction of depressiv...
Humans are exposed to a multitude of environmental chemical mixtures (ECMs) in daily life that may influence depression risk. While prior studies have shown individual ECM exposures to depression, the cumulative and interactive effects of multiple co...
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