Biomarker and clinical data-based predictor tool (MAUXI) for ultrafiltration failure and cardiovascular outcome in peritoneal dialysis patients: a retrospective and longitudinal study.

Journal: BMJ health & care informatics
PMID: 40021191

Abstract

OBJECTIVES: To develop a machine learning-based software as a medical device to predict the endurance and outcomes of peritoneal dialysis (PD) patients in real time using effluent-measured biomarkers of the mesothelial-to-mesenchymal transition (MMT).

Authors

  • Eva María Arriero-País
    Tissue and Organ Homeostasis Program, Cell-Cell Communication and Inflammation Unit, Centro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, Fundacion General CSIC, Madrid, Spain.
  • María Auxiliadora Bajo-Rubio
    Servicio de Nefrología, Hospital Universitario de la Princesa & Instituto de Investigación la Princesa (IP), Madrid, Spain.
  • Roberto Arrojo-García
    Tissue and Organ Homeostasis Program, Cell-Cell Communication and Inflammation Unit, Centro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, Fundacion General CSIC, Madrid, Spain.
  • Pilar Sandoval
    Tissue and Organ Homeostasis Program, Cell-Cell Communication and Inflammation Unit, Centro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, Fundacion General CSIC, Madrid, Spain.
  • Guadalupe Tirma González-Mateo
    Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS 2040-Renal), Madrid, Spain.
  • Patricia Albar-Vizcaíno
    Servicio de Nefrología, Hospital Universitario La Paz & Instituto de Investigación Sanitaria la Paz (IdiPAZ), Madrid, Spain.
  • Gloria Del Peso-Gilsanz
    Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS 2040-Renal), Madrid, Spain.
  • Marta Ossorio-González
    Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS 2040-Renal), Madrid, Spain.
  • Pedro Majano
    Unidad de Biología Molecular, Hospital Universitario de la Princesa & Instituto de Investigación la Princesa (IP), Madrid, Spain.
  • Manuel López-Cabrera
    Tissue and Organ Homeostasis Program, Cell-Cell Communication and Inflammation Unit, Centro de Biologia Molecular Severo Ochoa (CBM), CSIC-UAM, Fundacion General CSIC, Madrid, Spain mlcabrera@cbm.csic.es.

Keywords

External Resources

Popular Topics
Recent Journals