Annotation-Free Whole-Slide Image Analysis Method to Assess Immune Infiltration in Colorectal Cancer.
Journal:
JCO precision oncology
PMID:
40334155
Abstract
PURPOSE: Tumor-infiltrating lymphocytes (TILs) play a crucial role in host antitumor processes. High level of TILs is associated with better outcomes for patients. We aim to automatically quantify TILs without any nuclei annotation and further construct an immune score to predict the survival of patients with colorectal cancer.