BACKGROUND: Acute Myeloid Leukemia (AML) is a highly heterogeneous hematologic malignancy influenced by various factors affecting prognosis. Recently, the role of coagulation-related genes in tumor biology has garnered increasing attention. This stud...
BACKGROUND: Early detection of vulnerable carotid plaques is critical for stroke prevention. This study aimed to develop a machine learning model based on routine blood tests and derived indices to predict plaque vulnerability and assess sex-specific...
Idiopathic membranous nephropathy (IMN) is the major cause of autoimmune-related nephrotic syndrome. The role immune cells play in the risk and prognosis of IMN remains elusive. We employ multi-omics data and a variety of approaches to evaluate the c...
The mortality rates have been increasing for glioma in adolescents and young adults (AYAs, aged 15-39 years). However, current biomarkers for clinical assessment in AYAs glioma are limited, prompting the urgent need for identifying ideal prognostic s...
PURPOSE: To develop and validate a hybrid radiomics model to predict the overall survival in pancreatic cancer patients and identify risk factors that affect patient prognosis.
BACKGROUND: Hepatic encephalopathy (HE) contributes significantly to mortality among patients with liver cirrhosis. Early prediction of HE is essential for clinical decision-making, yet remains challenging-particularly in noncancer-related cirrhosis ...
BACKGROUND: Acute cholangitis (AC) presents with significant clinical heterogeneity, and existing severity classifications have limited prognostic value in critically ill patients. Subtypes of AC in critically ill patients have not been investigated.
BACKGROUND: Nonspecific orbital inflammation (NSOI), also known as idiopathic orbital inflammation, comprises a heterogeneous group of immune-mediated disorders affecting orbital tissues, unified by the absence of a defined etiology. Lactotransferrin...
Prostate cancer (PCa) is the most prevalent malignant tumor in males, and many patients remain at risk of biochemical recurrence (BCR) following initial treatment. Accurate prediction of BCR is vital for effective clinical management and treatment pl...
Current first-line treatments of paediatric ulcerative colitis (UC) maintain a 6-month remission in only half of the patients. Relapse prediction at diagnosis could enable earlier introduction of immunosuppressants. We collected intestinal biopsies f...
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