ABVS breast tumour segmentation via integrating CNN with dilated sampling self-attention and feature interaction Transformer.

Journal: Neural networks : the official journal of the International Neural Network Society
PMID:

Abstract

Given the rapid increase in breast cancer incidence, the Automated Breast Volume Scanner (ABVS) is developed to screen breast tumours efficiently and accurately. However, reviewing ABVS images is a challenging task owing to the significant variations in sizes and shapes of breast tumours. We propose a novel 3D segmentation network (i.e., DST-C) that combines a convolutional neural network (CNN) with a dilated sampling self-attention Transformer (DST). In our network, the global features extracted from the DST branch are guided by the detailed local information provided by the CNN branch, which adapts to the diversity of tumour size and morphology. For medical images, especially ABVS images, the scarcity of annotation leads to difficulty in model training. Therefore, a self-supervised learning method based on a dual-path approach for mask image modelling is introduced to generate valuable representations of images. In addition, a unique postprocessing method is proposed to reduce the false-positive rate and improve the sensitivity simultaneously. The experimental results demonstrate that our model has achieved promising 3D segmentation and detection performance using our in-house dataset. Our code is available at: https://github.com/magnetliu/dstc-net.

Authors

  • Yiyao Liu
    School of Biomedical Engineering, Health Science Centers, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Marshall Laboratory of Biomedical Engineering, Shenzhen University, Shenzhen, China.
  • Jinyao Li
    School of Pharmaceutical Sciences and Institute of Materia Medica & Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi, 830017, China.
  • Yi Yang
    Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Cheng Zhao
    Department of Urology, Xiangya Hospital, Central South University, Changsha 410008, China.
  • Yongtao Zhang
    Department of Information and Electronic Engineering, Shangqiu Institute of Technology, Shangqiu 476000, China.
  • Peng Yang
  • Lei Dong
  • Xiaofei Deng
    Department of Ultrasonics, Huazhong University of Science and Technology, Union Shenzhen Hospita, Shenzhen, 518000, Guangdong, China.
  • Ting Zhu
  • Tianfu Wang
    School of Biomedical Engineering, Shenzhen University Health Sciences Center, Shenzhen, Guangdong 518060, P.R.China.
  • Wei Jiang
    Department of Civil Engineering, Johns Hopkins System Institute, Johns Hopkins University, Baltimore, Maryland.
  • Baiying Lei