Development of model for identifying homologous recombination deficiency (HRD) status of ovarian cancer with deep learning on whole slide images.
Journal:
Journal of translational medicine
PMID:
40038690
Abstract
BACKGROUND: Homologous recombination deficiency (HRD) refers to the dysfunction of homologous recombination repair (HRR) at the cellular level. The assessment of HRD status has the important significance for the formulation of treatment plans, efficacy evaluation, and prognosis prediction of patients with ovarian cancer.