Deep learning models for improving Parkinson's disease management regarding disease stage, motor disability and quality of life.

Journal: Computers in biology and medicine
PMID:

Abstract

BACKGROUND AND OBJECTIVE: Motor diagnosis, monitoring and management of Parkinson's disease (PD) focuses mainly on observational methods and, clinical scales, resulting in a subjective evaluation. Inertial sensors combined with artificial intelligence have emerged as a promising solution to help physicians perform early, differential, and objective quantification of motor symptoms over time. We hypothesize that a long short-term memory-deep neural network (LSTM) architecture could be an appropriate solution for producing three models to provide a holistic assessment of patients with PD from a single inertial sensor.

Authors

  • Helena R Gonçalves
    Center for MicroElectroMechanical Systems, University of Minho, Guimarães, Portugal.
  • Pedro Pinheiro
    Center for MicroElectroMechanical Systems, University of Minho, Guimarães, Portugal.
  • Cristiana Pinheiro
    Center for MicroElectroMechanical Systems (CMEMS), Department of Industrial Electronics, School of Engineering, University of Minho, 4800-058 Guimarães, Portugal.
  • Luís Martins
    Center for MicroElectroMechanical Systems, University of Minho, Guimarães, Portugal.
  • Ana Margarida Rodrigues
    Neurology Service, Hospital of Braga, Portugal; Clinical Academic Center, Hospital of Braga, Portugal.
  • Cristina P Santos