[Nobel Prize in chemistry 2024: David Baker, Demis Hassabis et John M. Jumper. The revolution of artificial intelligence in structural biology].
Journal:
Medecine sciences : M/S
PMID:
40294296
Abstract
The 2024 Nobel Prize in chemistry has been awarded to Demis Hassabis and John M. Jumper (Google DeepMind) for the development of artificial intelligence-guided protein structure prediction and to David Baker (University of Washington, Seattle, USA) for the development of computational protein design. This event marks a revolution in the field of structural biology that has led, among other things, to the generation of a library of nearly 200 million predicted protein structures designed to speed up research. This revolution in AI has also led to the design of several artificial proteins of medical interest presented in this review.