Portable ECG and PCG wireless acquisition system and multiscale CNN feature fusion Bi-LSTM network for coronary artery disease diagnosis.

Journal: Computers in biology and medicine
PMID:

Abstract

Coronary artery disease (CAD) is a major cause of mortality, especially among aging populations, making timely and accurate diagnosis essential. In this work, a portable wireless device powered by artificial intelligence for CAD detection is proposed, which synchronously captures electrocardiograms (ECG) and phonocardiograms (PCG) signals and transmits them for real-time analysis and visualization. To ensure the reliability of the acquired signals, a Hidden Semi Markov model is applied to validate data quality. Then, a multiscale convolutional neural network (CNN) feature fusion model extracts critical features from the PCG and ECG signals. All these features and signal information are later processed by a bidirectional long short-term memory (Bi-LSTM) network. Our network achieves impressive metrics and maintains reliable performance in practical tests. This straightforward diagnostic system offers a practical and technically feasible solution for the effective diagnosis of CAD, leveraging advanced neural network architectures for robust clinical application.

Authors

  • Junye Lin
    Ministry of Education Key Lab. of RF Circuits and Systems, College of Electronics & Information Hangzhou Dianzi University, Hangzhou, China.
  • Shaokui Wang
    Ministry of Education Key Lab. of RF Circuits and Systems, College of Electronics & Information Hangzhou Dianzi University, Hangzhou, China.
  • Weipeng Xuan
    Ministry of Education Key Lab. of RF Circuits and Systems, College of Electronics & Information Hangzhou Dianzi University, Hangzhou, China. Electronic address: xuanweipeng@hdu.edu.cn.
  • Ding Chen
    Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing 211816, P. R. China.
  • Fuhai Liu
    Open FIESTA Center, Tsinghua University, Shenzhen, P.R. China.
  • Jinkai Chen
  • Shudong Xia
    Department of Heart Center, The Fourth Affiliated Hospital of Zhejiang University School of Medicine, N1 Shangcheng Road, Yiwu 322000, China.
  • Shurong Dong
    College of Information Science & Electronic Engineering, Zhejiang University, Hangzhou 310027, China.
  • Jikui Luo
    College of Information Science and Electronic Engineering, Zhejiang University, Hangzhou 310027, China.