Multi-level feature fusion network for kidney disease detection.

Journal: Computers in biology and medicine
PMID:

Abstract

Kidney irregularities pose a significant public health challenge, often leading to severe complications, yet the limited availability of nephrologists makes early detection costly and time-consuming. To address this issue, we propose a deep learning framework for automated kidney disease detection, leveraging feature fusion and sequential modeling techniques to enhance diagnostic accuracy. Our study thoroughly evaluates six pretrained models under identical experimental conditions, identifying ResNet50 and VGG19 as the highly efficient models for feature extraction due to their deep residual learning and hierarchical representations. Our proposed methodology integrates feature fusion with an inception block to extract diverse feature representations while maintaining imbalance dataset overhead. To enhance sequential learning and capture long-term dependencies in disease progression, ConvLSTM is incorporated after feature fusion. Additionally, Inception block is employed after ConvLSTM to refine hierarchical feature extraction, further strengthening the proposed model ability to leverage both spatial and temporal patterns. To validate our approach, we introduce a new named Multiple Hospital Collected (MHC-CT) dataset, consisting of 1860 tumor and 1024 normal kidney CT scans, meticulously annotated by medical experts. Our model achieves 99.60 % accuracy on this dataset, demonstrating its robustness in binary classification. Furthermore, to assess its generalization capability, we evaluate the model on a publicly available benchmark multiclass CT scan dataset, achieving 91.31 % accuracy. The superior performance is attributed to the effective feature fusion using inception blocks and the sequential learning capabilities of ConvLSTM, which together enhance spatial and temporal feature representations. These results highlight the efficacy of the proposed framework in automating kidney disease detection, providing a reliable, and efficient solution for clinical decision-making. https://github.com/VS-EYE/KidneyDiseaseDetection.git.

Authors

  • Saif Ur Rehman Khan
    School of Computer Science and Engineering, Central South University, 932 Lushan S Rd, Yuelu District, Changsha, Hunan, China. Electronic address: saifurrehman.khan@csu.edu.cn.