Development, validation, and clinical evaluation of a machine-learning based model for diagnosing early infection after cardiovascular surgery (DEICS): a multi-center cohort study.

Journal: International journal of surgery (London, England)
PMID: 39903565

Abstract

BACKGROUND: This study addresses the critical need for timely and accurate diagnosis of early postoperative infection (EPI) following cardiac surgery. EPI significantly impacts patient outcomes and healthcare costs, making its early detection vital.

Authors

  • Tuo Pan
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
  • Haitao Zhang
    Graduate School, Hebei North University, 075000 Zhangjiakou, Hebei, China.
  • Chuangshi Wang
    National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
  • Hanghang Wang
    College of Life Science and Oceanography, Shenzhen University, Shenzhen 518060, China.
  • Yusanjian Matniyaz
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
  • Zhi-Kang Lv
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
  • Tong Tong Zhu
    Heart Center, Massachusetts General Hospital, Harvard University, Boston, USA.
  • Ya-Peng Wang
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Graduate School of Peking Union Medical College, Nanjing, China.
  • Zhi-Zhao Song
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
  • Yu-Xian Tang
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China.
  • He Zhang
    College of Natural Resources and Environment, Northwest A&F University, Yangling, 712100, Shaanxi, PR China; Key Laboratory of Plant Nutrition and the Agri-environment in Northwest China, Ministry of Agriculture and Rural Affairs, Yangling, 712100, Shaanxi, PR China.
  • Hao-Dong Pan
    Department of Clinical Medicine, Norman Bethune Health Science Center of Jilin University, Changchun, China.
  • Chen Li
    School of Computer Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, China.
  • Lin-Shan Yang
    Department of Critical Care Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.
  • Shi-Yu Guan
    Department of the Heart and Great Vessels, the affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China.
  • Wen Bian
    Department of the Heart and Great Vessels, the affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, China.
  • Xiateke Hafu
    Department of Cardio-Thoracic Surgery, Xinhua Hospital of Ili Kazak Autonomous Prefecture, Ili, China.
  • Xiang Li
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
  • Yang Li
    Occupation of Chinese Center for Disease Control and Prevention, Beijing, China.
  • Xiao-Ting Wu
    Department of Intensive Care Unit, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
  • Zhi-Wei Fan
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China.
  • Yuan-Xi Luo
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Graduate School of Peking Union Medical College, Nanjing, China.
  • Yi Jiang
    Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou 325035, China.
  • Ya-Xuan Gao
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
  • Wen-Zhe Wang
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
  • Yun-Xing Xue
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
  • Fu-Dong Fan
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
  • Jun Pan
    Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, College of Bioengineering, Chongqing University, Chongqing, China. Electronic address: panj@cqu.edu.cn.
  • Qing Zhou
    Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Bo-Min Zhang
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
  • Wei Wang
    State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China.
  • Qiang Wang
    Ningbo Konfoong Bioinformation Tech Co., Ltd, Ningbo, China.
  • Guo-Liang Fan
    Laboratory of Theoretical Biophysics, School of Physical Science and Technology, Inner Mongolia University, Hohhot 010021, China.
  • Dong-Jin Wang
    Department of Cardiac Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

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