Challenges and applications in generative AI for clinical tabular data in physiology.

Journal: Pflugers Archiv : European journal of physiology
PMID:

Abstract

Recent advancements in generative approaches in AI have opened up the prospect of synthetic tabular clinical data generation. From filling in missing values in real-world data, these approaches have now advanced to creating complex multi-tables. This review explores the development of techniques capable of synthesizing patient data and modeling multiple tables. We highlight the challenges and opportunities of these methods for analyzing patient data in physiology. Additionally, it discusses the challenges and potential of these approaches in improving clinical research, personalized medicine, and healthcare policy. The integration of these generative models into physiological settings may represent both a theoretical advancement and a practical tool that has the potential to improve mechanistic understanding and patient care. By providing a reliable source of synthetic data, these models can also help mitigate privacy concerns and facilitate large-scale data sharing.

Authors

  • Chaithra Umesh
    Institute of Computer Science, Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany. chaithra.umesh@uni-rostock.de.
  • Manjunath Mahendra
    Institute of Computer Science, Department of Systems Biology and Bioinformatics, University of Rostock, Rostock, Germany. manjunath.mahendra@uni-rostock.de.
  • Saptarshi Bej
    Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany.
  • Olaf Wolkenhauer
    Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany.
  • Markus Wolfien
    Department of Systems Biology and Bioinformatics, Institute of Computer Science, University of Rostock, Rostock, Germany.