AIMC Topic: Precision Medicine

Clear Filters Showing 1 to 10 of 1233 articles

From glycolytic signatures to patients: A translational roadmap for reproducible, equitable deployment of multi-omics and AI in colorectal cancer.

Medical oncology (Northwood, London, England)
Recent advances in Medical Oncology highlight the integration of bulk and single-cell transcriptomics to reveal glycolytic heterogeneity in colorectal cancer. Translating these discoveries into reliable clinical tools requires rigorous methods, trans...

Technologies, Clinical Applications, and Implementation Barriers of Digital Twins in Precision Cardiology: Systematic Review.

JMIR cardio
BACKGROUND: Digital twin systems are emerging as promising tools in precision cardiology, enabling dynamic, patient-specific simulations to support diagnosis, risk assessment, and treatment planning. However, the current landscape of cardiovascular d...

Personalized Machine Learning Intervention to Improve Sleep Quality Using Wearable Technology in Healthy Middle-Aged Adults From Mexico City: Protocol for a Pilot Randomized Controlled Trial.

JMIR research protocols
BACKGROUND: In 2019, global sleep surveys reported that 80% of adults want to improve their sleep quality, and in 2021, 45% were reported to be dissatisfied with their sleep. In 2025, among American adults, 37% reported sleep dissatisfaction and 38% ...

Neoantigen-driven cancer vaccines in personalized oncology: progress, obstacles, and translational prospects.

Molecular biology reports
The development of neoantigen-based cancer vaccines has emerged as a groundbreaking approach in the field of personalized oncology. Neoantigens, originating from tumor-specific somatic mutations, possess considerable immunogenic potential and are abs...

Artificial Intelligence Applications in the Diagnosis, Treatment, and Prognosis of Hepatocellular Carcinoma.

Gut and liver
The global burden of hepatocellular carcinoma (HCC) has shifted from viral to nonviral etiologies. However, successful antiviral therapy does not fully eliminate the risk of HCC, underscoring the demand for more effective surveillance strategies. Cur...

The Use of Artificial Intelligence for Personalized Treatment in Psychiatry.

Current psychiatry reports
PURPOSE OF REVIEW: This review examines the role of artificial intelligence (AI) in psychiatry in the past 5 years across four domains: screening; outcome prediction; risk and relapse prediction; and psychotherapy.

The role of gut microbiome in aging-associated diseases: where do we stand now and how technology will transform the future.

Gut microbes
The gut microbiome has emerged as a critical regulator of human aging and healthspan, with age-related dysbiosis increasingly implicated in a broad spectrum of aging-associated diseases. This review synthesizes evidence linking gut microbial alterati...

HepatoAI: Machine-Learning-Assisted Nano-enhanced Point-of-Care System for Personalized Precise Diagnosis of Hepatocellular Carcinoma.

Nano letters
Early diagnosis significantly improves survival rates for hepatocellular carcinoma (HCC), yet traditional methods face limitations, including specialized instruments/personnel and prolonged reporting cycles. While lateral flow immunoassay (LFA) offer...

Intelligent design of tumor microenvironment-responsive Adeno-associated virus vectors: overcoming delivery barriers and enabling precision therapy.

Medical oncology (Northwood, London, England)
Adeno-associated virus (AAV) has emerged as a pivotal vector for cancer gene therapy due to its low immunogenicity, non-pathogenicity, and sustained transgene expression capacity. However, the heterogeneity and complexity of the tumor microenvironmen...

Personalised medicine through AI-enhanced integration of diagnostic imaging and radiation therapy.

European radiology experimental
The integration of diagnostic imaging with radiation therapy (RT) is evolving into a continuous workflow, significantly advancing personalised oncology care. Recent technological innovations, particularly the incorporation of real-time magnetic reson...