Facial expression deep learning algorithms in the detection of neurological disorders: a systematic review and meta-analysis.

Journal: Biomedical engineering online
Published Date: May 22, 2025

Abstract

BACKGROUND: Neurological disorders, ranging from common conditions like Alzheimer's disease that is a progressive neurodegenerative disorder and remains the most common cause of dementia worldwide to rare disorders such as Angelman syndrome, impose a significant global health burden. Altered facial expressions are a common symptom across these disorders, potentially serving as a diagnostic indicator. Deep learning algorithms, especially convolutional neural networks (CNNs), have shown promise in detecting these facial expression changes, aiding in diagnosing and monitoring neurological conditions.

Authors

  • Shania Yoonesi
    Department of Psychology, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
  • Ramila Abedi Azar
    Laboratory for Robotic Research, Iran University of Science and Technology, Tehran, Iran.
  • Melika Arab Bafrani
    Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.
  • Shayan Yaghmayee
    Nervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, Iran.
  • Haniye Shahavand
    School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Majid Mirmazloumi
    Guilan University of Medical Science, Guilan, Iran.
  • Narges Moazeni Limoudehi
    Student Research Committee, School of Paramedical and Rehabilitation Sciences, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Mohammadreza Rahmani
    Student Research Committee, Zanjan University of Medical Sciences, Zanjan, Iran.
  • Saina Hasany
    Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
  • Fatemeh Zahra Idjadi
    Faculty of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
  • Mohammad Amin Aalipour
    Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Hossein Gharedaghi
    School of Medicine, Zanjan University of Medical Science, Zanjan, Iran.
  • Sadaf Salehi
    Student Research Committee, Iran University of Medical Sciences, Tehran, Iran.
  • Mahsa Asadi Anar
    Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Mohammad Saeed Soleimani
    Fasa University of Medical Science, Fars, Iran. Soliemani.saeed@gmail.com.

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