Early Disease Prediction Using a Text-Numerical Hybrid Model Using Large-Scale Clinical Real-World Data.

Journal: AMIA ... Annual Symposium proceedings. AMIA Symposium
Published Date:

Abstract

To assist physicians in predicting diseases, most natural language processing (NLP) models have focused on progress notes in electronic medical records with full descriptions from the initial stage of patient diagnosis to the final stage of discharge. However, accurately predicting diseases in the early stage using initial notes is challenging due to limited information. To address this, a text-numerical hybrid method is developed to improve disease prediction accuracy. The method identifies "Reliably predicted diseases (RPD)" that can be robustly predicted in the NLP and Random Forest models even if there are missing values in the numerical data or the amount of text data is small. Results show that, among the predicted disease groups of the two models, diseases matching the RPD are preferentially adopted and integrated. Precision@10 reveals that our developed method has a relatively higher accuracy of 67.0% than the traditional NLP model.

Authors

  • Ayaka Oka
    Graduate School of Dentistry, Osaka University, Suita, Japan.
  • Tatsuya Yamaguchi
    Fujitsu Limited, Kanagawa, Japan.
  • Masaki Ishihara
    Fujitsu Limited, Kanagawa, Japan.
  • Takayuki Baba
    Department of Ophthalmology and Visual Science, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Tatsuya Sato
    Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
  • Kazuki Iwamoto
    Fujitsu Limited, Kanagawa, Japan.
  • Ryo Iwamura
    Fujitsu Limited, Kanagawa, Japan.
  • Shigetaka Toma
    Fujitsu Limited, Kanagawa, Japan.
  • Kaho Ogura
    Fujitsu Limited, Kanagawa, Japan.
  • Masahiro Kimura
    Fujitsu Limited, Kanagawa, Japan.
  • Hokuto Morohoshi
    Department of Hygiene, Public Health and Preventive Medicine, Showa University School of Medicine, Tokyo, Japan.
  • Akio Nakamura
    National Center for Child Health and Development, Setagaya-ku, Tokyo, Japan.