Early-life and concurrent predictors of the healthy adolescent microbiome in a cohort study.

Journal: Genome medicine
PMID: 40340756

Abstract

BACKGROUND: The microbiome of adolescents is poorly understood, as are factors influencing its composition. We aimed to describe the healthy adolescent microbiome and identify early-life and concurrent predictors of its composition.

Authors

  • Hannah E Laue
    Department of Biostatistics and Epidemiology, University of Massachusetts Amherst School of Public Health and Health Sciences, 715 N. Pleasant Street, Arnold House 429, Amherst, MA, 01003, USA. hlaue@umass.edu.
  • Amy D Willis
    Department of Biostatistics, University of Washington Hans Rosling Center for Population Health, 3980 15 Avenue NE, Box 351617, Seattle, WA, 98195-1617, USA.
  • Fang Wang
    Key Laboratory of Intelligent Computing and Information Processing of Ministry of Education and Hunan Key Laboratory for Computation and Simulation in Science and Engineering, Xiangtan University, Xiangtan, China.
  • Melinda C MacDougall
    Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.
  • Yingying Xu
    Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.
  • Margaret R Karagas
    Department of Epidemiology, Dartmouth Geisel School of Medicine, One Medical Center Dr Lebanon, Lebanon, NH, 03756, USA.
  • Juliette C Madan
    Department of Epidemiology, Dartmouth Geisel School of Medicine, One Medical Center Dr Lebanon, Lebanon, NH, 03756, USA.
  • Abby F Fleisch
    Center for Interdisciplinary and Population Health Research, Maine Institute for Research, Westbrook, ME, USA.
  • Bruce P Lanphear
    Faculty of Health Sciences, Simon Fraser University, Blusson Hall, 8888 University Dr, Burnaby, BC, Canada.
  • Kim M Cecil
    Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.
  • Kimberly Yolton
    Division of General and Community Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.
  • Aimin Chen
    Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, 423 Guardian Drive, Philadelphia, PA, 19104, USA.
  • Jessie P Buckley
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, MD, USA.
  • Joseph M Braun
    Department of Epidemiology, Brown University, 121 S Main St, Providence, RI, USA.

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