μGlia-Flow, an automatic workflow for microglia segmentation and classification.

Journal: Journal of neuroscience methods
Published Date: Apr 10, 2025

Abstract

BACKGROUND: Microglia are important immune cells in the central nervous system, playing a key role in various pathological processes. The morphological diversity of microglia is closely linked to the development of brain diseases, yet accurate segmentation and automatic classification of microglia remain challenging.

Authors

  • Huangrui Xiong
    School of Information Science and Technology, MoE Key Laboratory of Brain-inspired Intelligent Perception and Cognition, CAS Key Laboratory of Brain Function and Disease, University of Science and Technology of China, Hefei, China; Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
  • Siling Zheng
    School of Information Science and Technology, MoE Key Laboratory of Brain-inspired Intelligent Perception and Cognition, CAS Key Laboratory of Brain Function and Disease, University of Science and Technology of China, Hefei, China.
  • Xiuhong Qi
    Institute of Artificial Intelligence, Hefei Comprehensive National Science Center, Hefei, China.
  • Ji Liu

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