Rapid wall shear stress prediction for aortic aneurysms using deep learning: a fast alternative to CFD.

Journal: Medical & biological engineering & computing
Published Date:

Abstract

Aortic aneurysms pose a significant risk of rupture. Previous research has shown that areas exposed to low wall shear stress (WSS) are more prone to rupture. Therefore, precise WSS determination on the aneurysm is crucial for rupture risk assessment. Computational fluid dynamics (CFD) is a powerful approach for WSS calculations, but they are computationally intensive, hindering time-sensitive clinical decision-making. In this study, we propose a deep learning (DL) surrogate, MultiViewUNet, to rapidly predict time-averaged WSS (TAWSS) distributions on abdominal aortic aneurysms (AAA). Our novel approach employs a domain transformation technique to translate complex aortic geometries into representations compatible with state-of-the-art neural networks. MultiViewUNet was trained on real and synthetic AAA geometries, demonstrating an average normalized mean absolute error (NMAE) of just in WSS prediction. This framework has the potential to streamline hemodynamic analysis in AAA and other clinical scenarios where fast and accurate stress quantification is essential.

Authors

  • Md Ahasan Atick Faisal
    Department of Electrical Engineering, Qatar University, Doha 2713, Qatar.
  • Onur Mutlu
    Department of Information Technology and Electrical Engineering, ETH Zürich, Zürich, Switzerland. omutlu@ethz.ch.
  • Sakib Mahmud
    Department of Electrical Engineering, Qatar University, Doha, 2713, Qatar.
  • Anas Tahir
    Department of Electrical Engineering, Qatar University, Doha, 2713, Qatar. Electronic address: a.tahir@qu.edu.qa.
  • Muhammad E H Chowdhury
    Department of Electrical Engineering, Qatar University, Doha 2713, Qatar.
  • Faycal Bensaali
    Department of Electrical Engineering, Qatar University, Doha, Qatar.
  • Abdulrahman Alnabti
    Heart Hospital, Hamad Medical Corporation, Doha, Qatar. Electronic address: aalnabti@hamad.qa.
  • Mehmet Metin Yavuz
    Department of Mechanical Engineering, Middle East Technical University, Ankara, 06800, Turkey.
  • Ayman El-Menyar
    Department of Surgery, Trauma Surgery, Clinical Research, Hamad Medical Corporation, Doha, Qatar.
  • Hassan Al-Thani
    Trauma Surgery, Hamad Medical Corporation, Doha, Qatar.
  • Huseyin Cagatay Yalcin
    Biomedical Research Center, Qatar University, Doha, 2713, Qatar. hyalcin@qu.edu.qa.