A neural network-shaped composite of α-MnO with N-doped graphene for electrocatalytic reduction of hydrogen peroxide in human urine samples.
Journal:
The Analyst
Published Date:
Jul 21, 2025
Abstract
A neural network-shaped composite fusing α-MnO and nitrogen-doped graphene (N@Gr/α-MnO) was synthesized a hydrothermal method. The resulting composite demonstrates enhanced electrocatalytic activity for hydrogen peroxide (HO) compared with each single component. The electrochemical sensor developed with N@Gr/α-MnO demonstrates a robust linear relationship over the concentration ranges of 0.05 μmol L to 0.625 mmol L and 0.77 to 8.27 mmol L, as evaluated by chronoamperometry (CA). The limit of detection (LOD) for HO was determined to be 1.4 × 10 mol L (S/N = 3), with a sensitivity of 1466.1 μA (mmol L) cm. Furthermore, the sensor has been successfully utilized to detect trace amounts of HO in human urine samples, thereby providing valuable insights and strategies for the development of more sensitive electrochemical sensors.
