Pyrethroid pesticide residues pose a significant global public health challenge, particularly in complex edible fungus matrices where trace, structurally similar pesticides are difficult to distinguish and detect. To address this critical gap, a nove...
The simultaneous determination of the expression levels of multiple inflammation-associated cytokines in blood holds great promise for the early screening of cancer including colorectal cancer (CRC). Herein, an antibody microarray-based sandwich meta...
Laser desorption-ionization mass spectrometry (LDI-MS) is prized for its rapidity, simplicity, low sample consumption, and high throughput in metabolic analysis, with great potential as a diagnostic tool. Herein, an LDI-MS method with sulfone-contain...
Investigations on epithelial-mesenchymal transition (EMT) events occurring on circulating tumor cells (CTCs) are poised to significantly advance nanoliquid biopsy methodologies. This study presented a colorimetric multiplex lateral flow immunoassay s...
This study develops an innovative approach that integrates a colorimetric sensor array (CSA) composed of phenylalanine-modified MnO nanozymes with advanced algorithms, aiming to detect the anthrax biomarker 2,6-pyridine dicarboxylic acid (2,6-PDA) an...
Timely and precise therapeutic drug monitoring (TDM) is critical for managing pharmacokinetic variability and optimizing individualized therapy, particularly during public health crises such as the COVID-19 pandemic. Herein, we optimized integrated m...
Urinary glucose, creatinine, and uric acid are vital biomarkers for diabetes and kidney disease management. However, multiplex point-of-care detection faces challenges due to insufficient sensitivity in complex urine matrices and signal cross-talk fr...
The intelligent authentication of whole wheat products remains a significant challenge due to the difficulty in simultaneously monitoring multiple alkylresorcinol (AR) homologues within complex food matrices. To address this, we have developed a nove...
Pathogenic bacteria pose serious threats to public health and environmental safety. Conventional colony counting, a standard method for bacterial detection, is time-consuming and unsuitable for rapid on-site detection. In this work, a flexible ACH/Ag...
Recently, the severe side effects related to the widespread consumption of antidepressants (ADs) have alarmingly created a global challenge for clinics and forensic laboratories. This study introduces a machine learning-empowered multicolor fluoresce...
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