Stakeholder Perspectives on Trustworthy AI for Parkinson Disease Management Using a Cocreation Approach: Qualitative Exploratory Study.

Journal: Journal of medical Internet research
Published Date: Aug 6, 2025

Abstract

BACKGROUND: Parkinson disease (PD) is the fastest-growing neurodegenerative disorder in the world, with prevalence expected to exceed 12 million by 2040, which poses significant health care and societal challenges. Artificial intelligence (AI) systems and wearable sensors hold potential for PD diagnosis, personalized symptom monitoring, and progression prediction. Nonetheless, ethical AI adoption requires several core principles, including user trust, transparency, fairness, and human oversight.

Authors

  • Beatriz Alves
    Faculdade de Motricidade Humana, University of Lisbon, Lisbon, Portugal.
  • Ghada Alhussein
  • Sara Riggare
    Participatory eHealth and Health Data Research Group, Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
  • Therese Scott Duncan
    Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
  • Ali Saad
    AINIGMA Technologies, Leuven, Belgium.
  • David M Lyreskog
    Neuroscience, Ethics & Society (NEUROSEC), Department of Psychiatry, University of Oxford, Oxford, United Kingdom.
  • Christos Chatzichristos
    STADIUS Center for Dynamical Systems, Signal Processing, and Data Analytics, Department of Electrical Engineering, KU Leuven, Leuven, Belgium.
  • Ioannis Gerasimou
    Department of Electrical Computer Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Stelios Hadjidimitriou
    Department of Electrical and Computer Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Leontios J Hadjileontiadis
    Department of Electrical and Computer Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece.
  • Sofia B Dias
    Center of Interdisciplinary Study of Human Perfomance (CIPER), Faculdade de Motricidade Humana, University of Lisbon, Lisbon, Portugal.

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