Construction of a feature gene and machine prediction model for inflammatory bowel disease based on multichip joint analysis.

Journal: Journal of translational medicine
Published Date: Aug 19, 2025

Abstract

BACKGROUND: Inflammatory bowel disease (IBD) is a chronic nonspecific inflammatory disorder triggered by immune responses and genetic factors. Currently, there is no cure for IBD, and its etiology remains unclear. As a result, early detection and diagnosis of IBD pose significant challenges. Therefore, investigating biomarkers in peripheral blood is highly important, as they can assist doctors in the early identification and management of IBD.

Authors

  • Yan Chaosheng
    Department of Gastroenterology, Affiliated Hospital of Jiangnan University, 214122, Wuxi city, Jiangsu Province, China.
  • Sun Haowen
    Wuxi Medical College, Jiangnan University, 214062, Wuxi City, Jiangsu Province, China.
  • Rao Jingjing
    Department of Gastroenterology, Affiliated Hospital of Jiangnan University, 214122, Wuxi city, Jiangsu Province, China.
  • Dai Yuanyuan
    Wuxi Medical College, Jiangnan University, 214062, Wuxi City, Jiangsu Province, China.
  • Duan Wenhui
    Wuxi Medical College, Jiangnan University, 214062, Wuxi City, Jiangsu Province, China.
  • Sheng Yingyue
    Department of Gastroenterology, Affiliated Hospital of Jiangnan University, 214122, Wuxi city, Jiangsu Province, China.
  • Xue Yuzheng
    Department of Gastroenterology, Affiliated Hospital of Jiangnan University, 214122, Wuxi city, Jiangsu Province, China. xueyz001@163.com.

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